SCHEMBL3469993

SCHEMBL3469993

Cc1cc(C(C)(C)C)c(OC(c2cc(C(C)(C)C)c(C)cc2C(C)(C)C)C(CO)(CO)CO)cc1C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.33
ALOX15 P16050 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2701190 0.96 TP53 (0.31) TP53ALOX15CYP2D6CYP2C9CYP2C19
SCHEMBL6702399 0.91 TP53 (0.30) TP53ALOX15CYP2D6CYP2C9CYP2C19
Pyrophosphoric Acid SCHEMBL28484906 0.90
SCHEMBL7107603 0.90 LMNA (0.34) TP53ALOX15LMNACYP3A4HPGD
SCHEMBL1075009 0.88
SCHEMBL2701189 0.88
SCHEMBL1075008 0.80
SCHEMBL9355933 0.79
SCHEMBL9251297 0.76 MRGPRX4 (0.38) TP53CYP2C9
SCHEMBL302380 0.76 USP2 (0.38) TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111892769-A Ultraviolet-resistant polypropylene composite material composition, application thereof and preparation method of ultraviolet-resistant polypropylene composite material 国家能源集团宁夏煤业有限责任公司 2020-11-06 CN disclosed
EP-2677003-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Chemical Corporation (JP) 2013-12-25 EP disclosed
EP-2230276-A1 POLYAMIDE RESIN MOLDING MATERIAL AND LAMINATE USING THE SAME Ube Industries, Ltd. (JP) 2010-09-22 EP disclosed
EP-2009057-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED PLATE OBTAINED THEREFROM Idemitsu Kosan Co., Ltd. (JP) 2008-12-31 EP disclosed
EP-1027348-B1 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLES USED AS U.V. STABILISERS GREAT LAKES CHEMICAL EUROP (CH) 2003-07-30 EP disclosed
EP-1049690-B1 s-(2'-HYDROXYPHENYL) BENZOTRIAZOLES CONTAINING A 2,4-IMIDAZOLIDINEDIONE GROUP AND PROCESS FOR THEIR PREPARATION GREAT LAKES CHEMICAL EUROP (CH) 2003-04-02 EP disclosed
EP-0867435-B1 2-(2'Hydroxyphenyl) benzotriazoles and their use as light stabilizers for organic polymers GREAT LAKES CHEMICAL EUROP (CH) 2003-01-08 EP disclosed
US-6452018-B1 HEAT, OXYGEN AND LIGHT, ESPECIALLY ULTRAVIOLET RADIATION, STABILIZERS FOR ORGANIC POLYMERS GREAT LAKES CHEMICAL ITALIA S. R. L. (IT) 2002-09-17 US disclosed
US-6407254-B1 FOR ORGANIC POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2002-06-18 US disclosed
US-6353044-B1 PHOTOSTABILITY OF POLYMER WITH BETA-(2,2,6,6-TETRAMETHYL PIPERIDINE-4-AMINO)ETHYL CROTONATE GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) 2002-03-05 US disclosed
US-6268505-B1 REACTING 2-(2'HYDROXYPHENYL) BENZOTRIAZOLES DERIVATIVE WITH PREPARATION 2,4-IMIDAZOLIDIONE-1,3-DIMETHYLOL COMPOUND OR 2,4-IMIDAZOLIDINEDIENE-1-METHYLOL COMPOUND IN PRESENCE OF TOLUENE OR P-TOLUENESULFONIC ACID AS CATALYST AND HEATING GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2001-07-31 US disclosed
US-6121456-A LIGHT STABILIZERS FOR POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2000-09-19 US disclosed
EP-0867435-A1 2-(2'Hydroxyphenyl) benzotriazoles and their use as light stabilizers for organic polymers GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) 1998-09-30 EP disclosed
US-5488112-A STABILIZERS FOR ORGANIC POLYMERS AGAINST HEAT. LIGHT AND OXYGEN CIBA-GEIGY CORPORATION (US) 1996-01-30 US disclosed