SCHEMBL9251297

SCHEMBL9251297

Cc1ccc(C(C)(C)C)c(OC(c2cc(C)ccc2C(C)(C)C)C(CO)(CO)CO)c1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.38
HTT P42858 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 2/20 0.37
LPAR1 Q92633 1/20 0.32
CYP2C9 P11712 1/20 0.31
TP53 P04637 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL226925 0.83 EGFR (0.33) L3MBTL1CYP2C9
SCHEMBL302380 0.81 USP2 (0.38) MRGPRX4HTTL3MBTL1TP53USP2
SCHEMBL28929215 0.77 USP2 (0.36) HTTL3MBTL1KDM4ETP53USP2
SCHEMBL7107603 0.77 LMNA (0.34) TP53
SCHEMBL3469993 0.76 TP53 (0.33) CYP2C9TP53
SCHEMBL6702399 0.76 TP53 (0.30) CYP2C9TP53
SCHEMBL1030791 0.75 ALDH1A1 (0.39) HTTL3MBTL1KDM4ETP53
SCHEMBL26092351 0.74 MRGPRX4 (0.32) MRGPRX4LPAR1
SCHEMBL2701190 0.73 TP53 (0.31) CYP2C9TP53
SCHEMBL1075009 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0226453-B2 Polyolefin composition SUMITOMO CHEMICAL CO (JP) 1995-07-26 EP disclosed
EP-0226453-A2 Polyolefin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-06-24 EP disclosed
EP-0074090-B1 POLYMER STABILIZERS BORG-WARNER CHEMICALS INC. (US) 1985-09-04 EP disclosed
EP-0074090-A2 Polymer stabilizers BORG-WARNER CHEMICALS INC. (US) 1983-03-16 EP disclosed
US-4376857-A HEAT STABILIZERS FOR POLYMERS BORG-WARNER CORPORATION (US) 1983-03-15 US disclosed
US-4287339-A AS STABILIZERS FOR OLEFIN POLYMERS BORG-WARNER CORPORATION (US) 1981-09-01 US disclosed