Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | RORC | P51449 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695939 | 0.94 | RORC (0.54) | DRD2RORCCCR1 | |
| SCHEMBL655150 | 0.94 | DRD2 (0.56) | DRD2MEN1KMT2AKDM4ESTS | |
| SCHEMBL19462827 | 0.87 | RORC (0.50) | DRD2RORCMEN1KMT2A | |
| SCHEMBL1430196 | 0.87 | RORC (0.50) | DRD2RORCMEN1KMT2A | |
| SCHEMBL557597 | 0.86 | DRD2 (0.61) | DRD2MEN1KMT2AKDM4ESTS | |
| SCHEMBL1199600 | 0.86 | RORC (0.51) | DRD2RORCCCR1 | |
| SCHEMBL1983281 | 0.84 | MEN1 (0.52) | DRD2RORCMEN1KMT2ASTS | |
| SCHEMBL569651 | 0.84 | RORC (0.55) | DRD2RORC | |
| SCHEMBL31084071 | 0.84 | MEN1 (0.52) | DRD2RORCMEN1KMT2AKDM4E | |
| SCHEMBL21837034 | 0.82 | RORC (0.51) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077915-A1 | NOVEL COMPOUNDS USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-07-08 | — | — | WO | disclosed |