Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 10/20 | 0.39 |
| ▸ | NMT1 | P30419 | 10/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.35 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470363 | 0.85 | NMT2 (0.41) | NMT2NMT1L3MBTL1 | |
| SCHEMBL6869762 | 0.80 | NMT2 (0.61) | NMT2NMT1 | |
| SCHEMBL6872151 | 0.78 | NMT2 (0.40) | NMT2NMT1 | |
| SCHEMBL6870822 | 0.78 | NMT2 (0.44) | NMT2NMT1 | |
| SCHEMBL6871587 | 0.77 | NMT2 (0.59) | NMT2NMT1 | |
| SCHEMBL6863486 | 0.77 | NMT2 (0.59) | NMT2NMT1 | |
| SCHEMBL6873892 | 0.76 | NMT2 (0.50) | NMT2NMT1 | |
| SCHEMBL6863890 | 0.76 | NMT2 (0.43) | NMT2NMT1 | |
| SCHEMBL7882840 | 0.76 | KDM4E (0.43) | NMT2NMT1L3MBTL1KDM4ECYP3A4 | |
| SCHEMBL6873441 | 0.76 | NMT2 (0.51) | NMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | claimed |
| WO-2010134939-A2 | MAMMALIAN GENES INVOLVED IN INFECTION | Zirus, Inc. (US) | 2010-11-25 | — | — | WO | disclosed |