SCHEMBL3470540

SCHEMBL3470540

C=CCc1ccc(OP(Oc2ccc(CC=C)c(CC=C)c2CC=C)Oc2ccc(CC=C)c(CC=C)c2CC=C)c(CC=C)c1CC=C

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
SRD5A1 P18405 2/20 0.33
GABRA1 P14867 4/20 0.33
GABRB2 P47870 4/20 0.33
ALOX5 P09917 4/20 0.33
KDM4E B2RXH2 2/20 0.33
CNR2 P34972 2/20 0.33
HPGD P15428 1/20 0.33
PTGDR Q13258 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ELANE P08246 1/20 0.31
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276594 0.86 PTGDR (0.34) ALDH1A1PPARGPPARDPPARASRD5A1
SCHEMBL728363 0.84 ALDH1A1 (0.37) ALDH1A1PPARGPPARDPPARASRD5A1
SCHEMBL1239929 0.84 GABRA1 (0.42) ALDH1A1GABRA1GABRB2KDM4EELANE
SCHEMBL1268594 0.81 ALDH1A1 (0.41) ALDH1A1GABRA1GABRB2KDM4E
SCHEMBL1918099 0.79 GABRA1 (0.43) ALDH1A1PPARGPPARDPPARASRD5A1
SCHEMBL2938725 0.78 GABRA1 (0.36) ALDH1A1PPARGPPARDPPARASRD5A1
SCHEMBL5690510 0.76 ALDH1A1 (0.38) ALDH1A1PPARGPPARDPPARASRD5A1
SCHEMBL2938726 0.75 PTGDR (0.34) ALDH1A1PPARGPPARDPPARASRD5A1
SCHEMBL460955 0.75 ALDH1A1 (0.34) ALDH1A1PPARGPPARDPPARASRD5A1
SCHEMBL725754 0.75 ALDH1A1 (0.47) ALDH1A1GABRA1GABRB2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5219937-A In presence of phosphite ALLIEDSIGNAL INC. (US) 1993-06-15 US claimed
EP-0227948-B1 IMPROVED PHOSPHITE STABILIZER COMPOSITIONS GE SPECIALTY CHEMICALS, INC. (US) 1993-04-07 EP claimed
EP-0017199-B2 WATER-DISPERSIBLE URETHANE POLYMERS AND AQUEOUS POLYMER DISPERSIONS TEXTRON INC. (US) 1987-12-23 EP claimed
EP-0227948-A2 Improved phosphite stabilizer compositions GE SPECIALTY CHEMICALS, INC. (US) 1987-07-08 EP claimed
EP-0017199-B1 WATER-DISPERSIBLE URETHANE POLYMERS AND AQUEOUS POLYMER DISPERSIONS TEXTRON INC. (US) 1984-07-04 EP claimed
US-4268426-A Water-dispersible urethane polymers, aqueous polymer dispersions and half-esters useful therein TEXTRON, INC. (US) 1981-05-19 US claimed
EP-0018665-A2 Urethane polymers and polymer dispersions TEXTRON INC. (US) 1980-11-12 EP claimed
EP-0017199-A1 Water-dispersible urethane polymers and aqueous polymer dispersions TEXTRON INC. (US) 1980-10-15 EP claimed
US-3980739-A Method of purifying triaryl phosphites RHONE-POULENC INDUSTRIES (FR) 1976-09-14 US claimed
JP-8337778-A None JP disclosed
JP-7309884-A None JP disclosed
EP-1910455-B1 STABILIZATION OF POLYOLEFINS WITH LIQUID TRIS-(MONO-ALKYL)PHENYL PHOSPHITES BASF SE (DE) 2012-08-08 EP disclosed
WO-2010069986-A1 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2010-06-24 WO disclosed
US-7468410-B2 Adding tris-(sec-butylphenyl)phosphite to polyolefin (low density polyethylene) for stabilizing against the deleterious effects of melt processing, heat aging and exposure to combustion products-of natural gas CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-12-23 US disclosed
US-4448969-A Cyclic ether or carbonate alkylation products of 2,2,5,5-tetramethylimidazolidin-4-one and derivatives, their preparation, and their use as stabilizers for _synthetic polymers FERRO CORPORATION (US) 1984-05-15 US disclosed
EP-0018665-B1 URETHANE POLYMERS AND POLYMER DISPERSIONS TEXTRON INC. (US) 1983-09-28 EP disclosed
US-4329490-A Water-dispersible urethane polymers, aqueous polymer dispersions and half-esters useful therein TEXTRON, INC. (US) 1982-05-11 US disclosed
US-4268426-A Water-dispersible urethane polymers, aqueous polymer dispersions and half-esters useful therein TEXTRON, INC. (US) 1981-05-19 US disclosed
EP-0018665-A2 Urethane polymers and polymer dispersions TEXTRON INC. (US) 1980-11-12 EP disclosed
EP-0017199-A1 Water-dispersible urethane polymers and aqueous polymer dispersions TEXTRON INC. (US) 1980-10-15 EP disclosed