Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568018 | 0.89 | MAPT (0.66) | MAPTKMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL6276416 | 0.86 | MAPT (0.62) | MAPTKMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL3132688 | 0.86 | MAPT (0.62) | MAPTKMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL5755306 | 0.84 | MAPT (0.60) | MAPTKMT2ATSHRCYP1A2CYP3A4 | |
| Veratric Acid Methyl Ester SCHEMBL2050732 | 0.84 | MAPT (0.86) | MAPTKMT2ATSHRCYP1A2CYP3A4 | |
| Veratric Acid Methyl Ester SCHEMBL29573244 | 0.84 | MAPT (0.86) | MAPTKMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL3738587 | 0.84 | MAPT (0.64) | MAPTKMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL18031241 | 0.83 | MAPT (0.59) | MAPTKMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL6622310 | 0.83 | MAPT (0.59) | MAPTKMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL20630574 | 0.83 | MAPT (0.59) | MAPTKMT2ATSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746242-A | Synthesis method of 6, 7-substituent-4-aniline quinazoline | OMEGA CO LTD | 2012-10-24 | — | — | CN | disclosed |
| CN-101863844-B | Synthesis method of 6, 7-substituent-4-aniline quinazoline | XIANGZHEN BIOLOGY TECHNOLOGY CO LTD | 2012-10-03 | — | — | CN | disclosed |
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | OMEGA MEDICAL TAIWAN LIMITED (TW) | 2010-10-21 | — | — | US | disclosed |
| CN-101863844-A | Synthesis method of 6, 7-substituent-4-aniline quinazoline | XIANGZHEN BIOLOGY TECHNOLOGY CO LTD | 2010-10-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | NQO2, ATIC, CYP3A7 | MAPT 3826/4885KMT2A 2686/4885TSHR 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.