Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 16/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470247 | 0.91 | EPHX2 (0.58) | EPHX2PPARGROCK2ROCK1 | |
| SCHEMBL13112865 | 0.85 | HPGD (0.56) | ROCK2ROCK1 | |
| SCHEMBL2969531 | 0.84 | EPHX2 (0.52) | EPHX2PPARGROCK2ROCK1 | |
| SCHEMBL2927034 | 0.83 | EPHX2 (0.55) | EPHX2PPARGROCK2ROCK1 | |
| SCHEMBL2901231 | 0.80 | EPHX2 (0.53) | EPHX2PPARGROCK2ROCK1 | |
| SCHEMBL13504959 | 0.79 | SCD5 (0.52) | — | |
| SCHEMBL1787178 | 0.79 | EPHX2 (0.52) | EPHX2PPARGROCK2 | |
| Hydrochloric Acid SCHEMBL3606790 | 0.79 | SCD5 (0.51) | — | |
| SCHEMBL3737330 | 0.78 | PTPN1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL3729498 | 0.77 | PTPN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261743-A1 | NOVEL SEH INHIBITORS AND THEIR USE | GLAXOSMITHKLINE LLC | 2010-10-14 | — | — | US | disclosed |
| US-20100261743-A1 | NOVEL SEH INHIBITORS AND THEIR USE | GLAXOSMITHKLINE LLC | 2010-10-14 | — | — | US | disclosed |
| WO-2009073772-A1 | NOVEL SEH INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261743-A1 | NOVEL SEH INHIBITORS AND THEIR USE | EPHX1, REN, NCEH1 | EPHX2 9/4885PPARG 3681/4885ROCK2 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.