Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065371 | 0.76 | KMT2A (0.56) | KMT2AKDM4EALDH1A1PPARGPPARA | |
| SCHEMBL401803 | 0.75 | CREBBP (0.58) | ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL3169119 | 0.74 | KMT2A (0.57) | KMT2AKDM4EALDH1A1PPARGPPARA | |
| SCHEMBL402819 | 0.74 | CNR1 (0.59) | ALDH1A1LMNA | |
| SCHEMBL17063908 | 0.73 | TUBB4A (0.44) | KDM4EALDH1A1MAPTRXFP1 | |
| SCHEMBL20037232 | 0.73 | KMT2A (0.56) | KMT2AKDM4EALDH1A1PPARGPPARA | |
| SCHEMBL12875609 | 0.73 | KMT2A (0.56) | KMT2AKDM4EALDH1A1PPARGPPARA | |
| SCHEMBL30052151 | 0.73 | KMT2A (0.56) | KMT2AKDM4EALDH1A1PPARGPPARA | |
| SCHEMBL3174313 | 0.73 | KMT2A (0.56) | KMT2AKDM4EALDH1A1PPARGPPARA | |
| SCHEMBL3471404 | 0.73 | GCGR (0.48) | KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113796-A1 | INDOLE DERIVATIVES AS S1P1 RECEPTOR | GLAXO GROUP LIMITED | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113796-A1 | INDOLE DERIVATIVES AS S1P1 RECEPTOR | S1PR1, S1PR3, S1PR2 | KMT2A 2344/4885KDM4E 3298/4885ALDH1A1 1154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.