Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 1.00 |
| ▸ | FNTB | P49356 | 3/20 | 1.00 |
| ▸ | CRYAB | P02511 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | CRYAA | P02489 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clavaric Acid SCHEMBL8897544 | 1.00 | FNTA (1.00) | FNTAFNTBCRYABMAPTMEN1 | |
| SCHEMBL29934605 | 0.87 | FNTA (0.77) | FNTAFNTBCRYABMAPTCRYAA | |
| Clavarinone SCHEMBL606234 | 0.83 | FNTA (1.00) | FNTAFNTBCRYABMAPTMEN1 | |
| Clavarinone SCHEMBL606233 | 0.83 | FNTA (1.00) | FNTAFNTBCRYABMAPTMEN1 | |
| SCHEMBL15934993 | 0.78 | CRYAB (0.78) | FNTAFNTBCRYABMAPTMEN1 | |
| SCHEMBL29934735 | 0.75 | FNTA (0.60) | FNTAFNTBCRYABMAPTCRYAA | |
| SCHEMBL5664605 | 0.75 | USP2 (0.73) | FNTAFNTBCRYABMAPTCRYAA | |
| SCHEMBL29692186 | 0.73 | CRYAB (0.77) | FNTAFNTBCRYABMAPTCRYAA | |
| SCHEMBL17428538 | 0.73 | FNTA (0.67) | FNTAFNTBCRYABMAPTCRYAA | |
| SCHEMBL17431762 | 0.73 | CRYAB (0.77) | FNTAFNTBCRYABMAPTCRYAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996035707-A1 | TERPENOID INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-11-14 | — | — | WO | claimed |
| WO-2010134939-A2 | MAMMALIAN GENES INVOLVED IN INFECTION | Zirus, Inc. (US) | 2010-11-25 | — | — | WO | disclosed |
| US-5703067-A | USEFUL IN THE TREATMENT OF CANCER | MERCK & CO., INC. (US) | 1997-12-30 | — | — | US | disclosed |
| WO-1996035707-A1 | TERPENOID INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-11-14 | — | — | WO | disclosed |