SCHEMBL29934735

SCHEMBL29934735

C[C@H](CC[C@@H](O)C(C)(C)O)[C@H]1CC[C@@]2(C)C3=C(C[C@H](O)[C@]12C)[C@@]1(C)C[C@@H](OC(=O)CC(C)(O)CC(=O)O)[C@H](O)C(C)(C)C1CC3

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.60
FNTB P49356 2/20 0.60
CRYAB P02511 4/20 0.39
CRYAA P02489 1/20 0.38
ACHE P22303 2/20 0.38
HSD11B1 P28845 1/20 0.36
HSD11B2 P80365 1/20 0.36
USP2 O75604 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP3A4 P08684 2/20 0.35
MAPT P10636 2/20 0.35
ALOX15 P16050 2/20 0.35
LMNA P02545 1/20 0.34
PRKAG1 P54619 1/20 0.33
PRKAA2 P54646 1/20 0.33
PRKAB1 Q9Y478 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29934605 0.88 FNTA (0.77) FNTAFNTBCRYABCRYAAUSP2
SCHEMBL29934612 0.83 FNTA (0.44) FNTAFNTBCRYABCRYAAACHE
SCHEMBL30584473 0.79 FNTA (0.46) FNTAFNTBCRYABCRYAAACHE
SCHEMBL29934953 0.77 FNTA (0.46) FNTAFNTBCRYABCRYAAACHE
Clavaric Acid SCHEMBL8897544 0.75 FNTA (1.00) FNTAFNTBCRYABCRYAAACHE
Clavaric Acid SCHEMBL3471580 0.75 FNTA (1.00) FNTAFNTBCRYABCRYAAACHE
SCHEMBL23699009 0.74 FNTA (0.45) FNTAFNTBCRYABCRYAAACHE
SCHEMBL29375258 0.74 FNTA (0.45) FNTAFNTBCRYABCRYAAACHE
Hebelomic Acid A SCHEMBL15944444 0.70 FNTA (0.36) FNTAFNTB
Hebelomic Acid A SCHEMBL20035914 0.70 FNTA (0.36) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS INC (US) 2025-10-16 US disclosed
EP-4522646-A2 APOE LIPOPROTEIN SYSTEMS Kisbee Therapeutics, Inc. (US) 2025-03-19 EP disclosed
WO-2023220387-A2 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed
US-20220291237-A1 Gene Expression Inflammatory Age and Its Uses Edifice Health, Inc. (US) 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS APOB, APOL1, LDLR FNTA 1865/4885FNTB 3113/4885CRYAB 630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.