Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3471744 | 1.00 | HPGD (0.59) | HPGDSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL15463039 | 1.00 | HPGD (0.59) | HPGDSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL22824610 | 0.90 | ALDH1A1 (0.54) | HPGDSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL30393930 | 0.89 | ALDH1A1 (0.52) | HPGDSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL10050296 | 0.89 | ALDH1A1 (0.52) | HPGDSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL7120261 | 0.87 | ALDH1A1 (0.51) | HPGDSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL7120256 | 0.87 | ALDH1A1 (0.51) | HPGDSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL2446290 | 0.87 | ALDH1A1 (0.75) | HPGDSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL12120526 | 0.87 | HSD17B10 (0.75) | HPGDSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL2446293 | 0.87 | ALDH1A1 (0.75) | HPGDSMN1; SMN2ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146135-A | Substituted pyrrole compound and preparation method and application thereof | 沈阳药科大学 | 2024-06-07 | — | — | CN | claimed |
| CN-106279027-A | (1 aryl 1H pyrazoles 4 base) (3,4,5 trimethoxyphenyl) ketone, ketoxime compounds and application thereof | 沈阳药科大学 | 2017-01-04 | — | — | CN | claimed |
| CN-118146135-A | Substituted pyrrole compound and preparation method and application thereof | 沈阳药科大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-118056820-A | 2, 4-Disubstituted thiophene compound and preparation method and application thereof | 沈阳药科大学 | 2024-05-21 | — | — | CN | disclosed |
| CN-114957123-B | 3- (difluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-114957124-B | 3- (trifluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-114957124-A | 3- (trifluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114957123-A | 3- (difluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-108794419-B | Naphtho [2,3-b ] isoxazole-4, 9-diketone derivative and preparation method and application thereof | 中南大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-106279056-B | (5-aryl-1, 2, 4-oxadiazole-3-yl) (3,4, 5-trimethoxyphenyl) -methanol, -ketone oxime compound and application thereof | 沈阳药科大学 | 2019-12-10 | — | — | CN | disclosed |
| CN-104382924-B | N6 substituted adenosines derivative and N6 substituted adenines derivatives and application thereof | 中国医学科学院药物研究所 | 2017-12-22 | — | — | CN | disclosed |
| CN-104744297-A | Anti-hepatitis B virus (HBV) activity phenylpropanoid benzaldehyde oxime ester type compounds | UNIV GUANGXI | 2015-07-01 | — | — | CN | disclosed |
| CN-104610230-A | Compounds for the treatment of cancer | UNIV TENNESSEE RES FOUNDATION | 2015-05-13 | — | — | CN | disclosed |
| CN-104592205-A | COMPOUNDS FOR TREATMENT OF CANCER | GTX INC | 2015-05-06 | — | — | CN | disclosed |
| CN-104382924-A | N6-substituted adenosine derivative and N6-substituted adenine derivative and application thereof | INST MATERIA MEDICA CAMS | 2015-03-04 | — | — | CN | disclosed |
| CN-102137592-B | Compounds for the treatment of cancer | UNIV TENNESSEE RES FOUNDATION (US) | 2015-01-28 | — | — | CN | disclosed |
| CN-103755664-A | 4-arylthia(selena)zole compounds and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2014-04-30 | — | — | CN | disclosed |
| CN-102030680-B | Novel oxime ether or ester derivatives with insecticidal activity | HUBEI ENGINEERING RES CT OF BIO PESTICIDE | 2014-03-26 | — | — | CN | disclosed |
| CN-102883607-A | Compounds for the treatment of cancer | GTX INC (US) | 2013-01-16 | — | — | CN | disclosed |
| WO-2010074776-A2 | COMPOUNDS FOR THE TREATMENT OF CANCER | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2010-07-01 | — | — | WO | disclosed |