Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15463039 | 0.89 | HPGD (0.59) | ALDH1A1KMT2AHTTMEN1HPGD | |
| SCHEMBL3471747 | 0.89 | HPGD (0.59) | ALDH1A1KMT2AHTTMEN1HPGD | |
| SCHEMBL3471744 | 0.89 | HPGD (0.59) | ALDH1A1KMT2AHTTMEN1HPGD | |
| SCHEMBL22824610 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2AHTTMEN1HPGD | |
| SCHEMBL30393930 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KMT2AHTTMEN1HPGD | |
| SCHEMBL7120261 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AHTTMEN1HPGD | |
| SCHEMBL2446290 | 0.81 | ALDH1A1 (0.75) | ALDH1A1KMT2AHTTMEN1HPGD | |
| SCHEMBL7120256 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AHTTMEN1HPGD | |
| SCHEMBL12120526 | 0.81 | HSD17B10 (0.75) | ALDH1A1KMT2AHTTMEN1HPGD | |
| SCHEMBL2446293 | 0.81 | ALDH1A1 (0.75) | ALDH1A1KMT2AHTTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083528-A1 | NOVEL PROTEIN KINASE MODULATORS AND THERAPEUTIC USES THEREOF | NOVOTYR THERAPEUTICS LTD. (IL) | 2012-04-05 | — | — | US | disclosed |
| US-8058309-B2 | Protein kinase modulators and therapeutic uses thereof | NOVOTYR THERAPEUTICS LTD. (IL) | 2011-11-15 | — | — | US | disclosed |
| US-20100056635-A1 | NOVEL PROTEIN KINASE MODULATORS AND THERAPEUTIC USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083528-A1 | NOVEL PROTEIN KINASE MODULATORS AND THERAPEUTIC USES THEREOF | PTK2B, LTK, MAP3K20 | ALDH1A1 4568/4885KMT2A 2629/4885HTT 2997/4885 |
| US-20100056635-A1 | NOVEL PROTEIN KINASE MODULATORS AND THERAPEUTIC USES THEREOF | PTK2B, LTK, FRK | ALDH1A1 4531/4885KMT2A 2718/4885HTT 3169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.