Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470606 | 0.89 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MAPK1THRBTP53 | |
| SCHEMBL4170825 | 0.88 | DPP4 (0.39) | MEN1KMT2ANPC1RAB9ADAGLA | |
| SCHEMBL4167405 | 0.88 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1MAPK1THRBTP53 | |
| SCHEMBL2517432 | 0.86 | PDE8B (0.41) | SMN1; SMN2ALDH1A1THRBTP53MEN1 | |
| SCHEMBL4157352 | 0.82 | MEN1 (0.40) | ALDH1A1TP53MEN1KMT2ARXFP1 | |
| SCHEMBL4163254 | 0.79 | DPP4 (0.39) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL3676086 | 0.77 | KDM4E (0.56) | SMN1; SMN2ALDH1A1MAPK1HPGDKDM4E | |
| SCHEMBL2512520 | 0.76 | PDE8B (0.42) | ALDH1A1MAPK1THRBTP53MEN1 | |
| SCHEMBL2124842 | 0.76 | PDE8B (0.40) | MEN1KMT2ALMNADAGLA | |
| SCHEMBL4159081 | 0.75 | KDM4E (0.42) | ALDH1A1TP53MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072722-A1 | PIPERIDINE DERIVATIVES USEFUL AS OREXIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2010-07-01 | — | — | WO | disclosed |