Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 7/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159081 | 0.87 | KDM4E (0.42) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL2123536 | 0.85 | METTL3 (0.48) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4170825 | 0.82 | DPP4 (0.39) | MEN1KMT2ANPC1RAB9ADAGLA | |
| SCHEMBL3472074 | 0.82 | SMN1; SMN2 (0.38) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8146332 | 0.80 | NPC1 (0.35) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4163082 | 0.75 | KDM4E (0.54) | ALDH1A1DAGLAABHD6KDM4EHSD17B10 | |
| SCHEMBL27808115 | 0.75 | KDM4E (0.54) | ALDH1A1DAGLAABHD6KDM4EHSD17B10 | |
| SCHEMBL2124328 | 0.73 | METTL3 (0.49) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3470606 | 0.72 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4629395 | 0.72 | HSD11B1 (0.61) | MEN1KMT2ANPC1RAB9ADAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090022670-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090022670-A1 | NOVEL COMPOUNDS | UGT1A1, UGT2B7, ABCB1 | MEN1 1727/4885KMT2A 3634/4885ALDH1A1 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.