SCHEMBL3472238

SCHEMBL3472238

Cc1ccccc1S(=O)(=O)OC(c1ccccc1)[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ ESR1 P03372 2/20 0.38
▸ ESR2 Q92731 2/20 0.38
▸ GAA P10253 1/20 0.38
▸ TBXAS1 P24557 2/20 0.37
▸ POLB P06746 2/20 0.37
▸ ALDH1A1 P00352 5/20 0.36
▸ ATM Q13315 1/20 0.36
▸ EDNRA P25101 2/20 0.35
▸ SLC1A3 P43003 1/20 0.35
▸ SLC1A2 P43004 1/20 0.35
▸ SLC1A1 P43005 1/20 0.35
▸ EDNRB P24530 1/20 0.34
▸ TP53 P04637 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ ALKBH2 Q6NS38 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3472235 0.78 NPY2R (0.44) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL4936612 0.74 MEN1 (0.44) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL14778954 0.74 MEN1 (0.44) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL11814147 0.74 CYP1A2 (0.37) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL6986846 0.74 GSR (0.43) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL27513395 0.73 CYP1A2 (0.36) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL9448466 0.73 ALDH1A1 (0.37) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL708291 0.72 ALDH1A1 (0.51) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL10360517 0.71 KMT2A (0.42) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL14779349 0.71 MEN1 (0.42) CYP1A2CYP2C9CYP2C19MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838602-B2 Weatherable, thermostable polymers having improved flow composition SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-11-23 — — US disclosed
US-7605221-B2 Aromatic polycarbonateester block or random copolymer and polysiloxane blend primarily containing isophthalic and terephthalic acids, resorcinol and dimethylsilanediol monomers; films are radiation transparent; improved ductility at lower temperatures; aircraft components SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-10-20 — — US disclosed
EP-2032624-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION Sabic Innovative Plastics IP B.V. (NL) 2009-03-11 — — EP disclosed
US-7432327-B2 Transparent polymeric compositions comprising polysiloxane-polycarbonate copolymer, articles made therefrom and methods of making same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-10-07 — — US disclosed
US-7321014-B2 Transparent compositions, methods for the preparation thereof, and articles derived therefrom GENERAL ELECTRIC COMPANY (US) 2008-01-22 — — US disclosed
WO-2008002757-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-03 — — WO disclosed
EP-1833919-A1 TRANSPARENT POLYMERIC COMPOSITIONS COMPRISING POLYSILOXANE-POLYCARBONATE COPOLYMER, ARTICLES MADE THEREFROM AND METHODS OF MAKING SAME General Electric Company (US) 2007-09-19 — — EP disclosed
EP-1833873-A2 TRANSPARENT COMPOSITIONS, METHODS FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM General Electric Company (US) 2007-09-19 — — EP disclosed
US-20070122627-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-05-31 — — US disclosed
US-20070027271-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-02-01 — — US disclosed
US-7169859-B2 Weatherable, thermostable polymers having improved flow composition GENERAL ELECTRIC COMPANY (US) 2007-01-30 — — US disclosed
WO-2006073901-A1 TRANSPARENT POLYMERIC COMPOSITIONS COMPRISING POLYSILOXANE-POLYCARBONATE COPOLYMER, ARTICLES MADE THEREFROM AND METHODS OF MAKING SAME GENERAL ELECTRIC COMPANY (US) 2006-07-13 — — WO disclosed
WO-2006071682-A2 TRANSPARENT COMPOSITIONS, METHODS FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2006-07-06 — — WO disclosed
US-20060148986-A1 Transparent polymeric compositions comprising polysiloxane-polycarbonate copolymer, articles made therefrom and methods of making same SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-07-06 — — US disclosed
US-20060142527-A1 Transparent compositions, methods for the preparation thereof, and articles derived therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-06-29 — — US disclosed
US-20050159577-A1 Weatherable, thermostable polymers having improved flow composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-07-21 — — US disclosed
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