Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1324567 | 0.83 | — | — | |
| Hydrazinecarboxamide SCHEMBL9859973 | 0.72 | TSHR (0.59) | CA5ACA5BCA2CA9 | |
| Nitric Acid SCHEMBL1173278 | 0.72 | CA5A (0.53) | CA5ACA5BTDP1CA2CA9 | |
| Nitric Acid SCHEMBL29270158 | 0.71 | MMP1 (0.39) | CA5ACA5B | |
| Urea SCHEMBL11151474 | 0.71 | CA5A (0.61) | CA5ACA5BTDP1 | |
| Urea SCHEMBL159340 | 0.71 | — | — | |
| Urea SCHEMBL11151480 | 0.71 | CA5A (0.61) | CA5ACA5BTDP1 | |
| Nitric Acid SCHEMBL28259983 | 0.70 | CA5A (0.44) | CA5ACA5BCA2CA9 | |
| Piperazine SCHEMBL8186673 | 0.70 | TDP1 (0.38) | TDP1 | |
| Nitric Acid SCHEMBL25282444 | 0.69 | CA5A (0.50) | CA5ACA5BCA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10044044-B2 | Cathode electrocatalyst and fuel cell | WIELAND FRIEDRICH WILHELM (DE) | 2018-08-07 | — | — | US | disclosed |
| US-20160118671-A1 | Cathode Electrocatalyst and Fuel Cell | WIELAND FRIEDRICH WILHELM (DE) | 2016-04-28 | — | — | US | disclosed |
| US-9276268-B2 | Electrocatalyst, fuel cell cathode and fuel cell | WIELAND FRIEDRICH WILHELM (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20130244133-A1 | Electrocatalyst, Fuel Cell Cathode and Fuel Cell | WIELAND FRIEDRICH WILHELM (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20100316931-A1 | Electrocatalyst, Fuel Cell Cathode and Fuel Cell | Wieland, Friedrich Wilhelm (DE) | 2010-12-16 | — | — | US | disclosed |