SCHEMBL3473480

SCHEMBL3473480

CC1(OP(=O)(c2ccccc2)c2ccccc2)CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA5A P35218 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31555940 0.72 NPSR1 (0.55) NPSR1MEN1KMT2AHIF1ASMN1; SMN2
SCHEMBL57952 0.70 NPSR1 (0.49) L3MBTL1NPSR1KMT2AHIF1ASMN1; SMN2
SCHEMBL9629605 0.69 TSHR (0.32) TSHR
SCHEMBL13066296 0.69 L3MBTL1 (0.44) L3MBTL1ALDH1A1NPSR1MEN1KMT2A
SCHEMBL13066297 0.69 L3MBTL1 (0.44) L3MBTL1ALDH1A1NPSR1MEN1KMT2A
SCHEMBL13066429 0.69 L3MBTL1 (0.44) L3MBTL1ALDH1A1NPSR1MEN1KMT2A
SCHEMBL10432441 0.69 KDM4E (0.38) ALDH1A1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL28203205 0.68 NPSR1 (0.37) NPSR1TSHR
SCHEMBL13672476 0.67 DRD2 (0.44) CA4
SCHEMBL1802975 0.67 NPSR1 (0.58) NPSR1HIF1ASMN1; SMN2CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7645851-B2 Polycarbonate with reduced color SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-12 US claimed
EP-2035500-A2 POLYCARBONATE WITH REDUCED COLOR Sabic Innovative Plastics IP B.V. (NL) 2009-03-18 EP claimed
WO-2008005655-A2 POLYCARBONATE WITH REDUCED COLOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-10 WO claimed
US-20080004379-A1 Polycarbonate with Reduced Color GENERAL ELECTRIC COMPANY (US) 2008-01-03 US claimed
US-8962788-B2 Production of a polycarbonate with limited metal residuals SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-02-24 US disclosed
WO-2014141108-A1 PRODUCTION OF A POLYCARBONATE WITH LIMITED METAL RESIDUALS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-09-18 WO disclosed
US-20140275466-A1 PRODUCTION OF A POLYCARBONATE WITH LIMITED METAL RESIDUALS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2014-09-18 US disclosed
EP-2041202-B1 METHOD FOR MAKING MOLDED POLYCARBONATE ARTICLES WITH IMPROVED COLOR SABIC INNOVATIVE PLASTICS IP (NL) 2013-05-08 EP disclosed
US-7645851-B2 Polycarbonate with reduced color SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-12 US disclosed
US-7541420-B2 Method for making molded polycarbonate articles with improved color SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-06-02 US disclosed
EP-2041202-A1 METHOD FOR MAKING MOLDED POLYCARBONATE ARTICLES WITH IMPROVED COLOR Sabic Innovative Plastics IP B.V. (NL) 2009-04-01 EP disclosed
EP-2035500-A2 POLYCARBONATE WITH REDUCED COLOR Sabic Innovative Plastics IP B.V. (NL) 2009-03-18 EP disclosed
WO-2008005633-A1 METHOD FOR MAKING MOLDED POLYCARBONATE ARTICLES WITH IMPROVED COLOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-10 WO disclosed
WO-2008005655-A2 POLYCARBONATE WITH REDUCED COLOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-10 WO disclosed
US-20080004379-A1 Polycarbonate with Reduced Color GENERAL ELECTRIC COMPANY (US) 2008-01-03 US disclosed
US-20080004407-A1 Molding polycarbonate resin made by a transesterification reaction using an activated diaryl carbonate such that the polycarbonate is susceptible to formation of internal ester linkages (IEL), and controlling (IEL) through incorporation of phosphite additive that inhibits the linkages GENERAL ELECTRIC COMPANY (US) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140275466-A1 PRODUCTION OF A POLYCARBONATE WITH LIMITED METAL RESIDUALS BMI1, EZH2, SUV39H2 L3MBTL1 1694/4885ALDH1A1 4642/4885NPSR1 2668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.