SCHEMBL3473632

SCHEMBL3473632

Nc1ccc2c(c1)Oc1cc(N)ccc1C2(C(F)(F)F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.42
MAPT P10636 4/20 0.38
KDM4E B2RXH2 4/20 0.38
MEN1 O00255 3/20 0.38
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 3/20 0.38
FTO Q9C0B1 1/20 0.38
GAA P10253 4/20 0.35
TSHR P16473 2/20 0.35
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
MAPK1 P28482 2/20 0.33
MITF O75030 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
NPC1 O15118 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30397838 1.00 PDK2 (0.42) PDK2MAPTKDM4EMEN1ALDH1A1
SCHEMBL30884612 0.85 PDK2 (0.41) PDK2MAPTKDM4EMEN1ALDH1A1
SCHEMBL8644400 0.77 FTO (0.44) PDK2MAPTMEN1ALDH1A1KMT2A
SCHEMBL30398085 0.76 PDK2 (0.43) PDK2MAPTKDM4EMEN1ALDH1A1
SCHEMBL3472059 0.76 PDK2 (0.43) PDK2MAPTKDM4EMEN1ALDH1A1
SCHEMBL22051892 0.72 MAPT (0.43) PDK2MAPTKDM4EMEN1ALDH1A1
SCHEMBL9455472 0.72 PDK2 (0.34) PDK2MAPTMEN1KMT2AFTO
SCHEMBL9732686 0.71 PDK2 (0.40) PDK2
SCHEMBL29617163 0.71 PDK2 (0.40) PDK2
SCHEMBL14182658 0.70 CYP3A4 (0.32) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2092807-B1 COMPOSITE ORGANIC ENCAPSULANTS CDA PROC LTD LIABILITY COMPANY (US) 2013-04-17 EP claimed
US-7745516-B2 Composition of polyimide and sterically-hindered hydrophobic epoxy E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-29 US claimed
US-20090111948-A1 Compositions comprising polyimide and hydrophobic epoxy and phenolic resins, and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2009-04-30 US claimed
EP-2027184-A2 HYDROPHOBIC COMPOSITIONS FOR ELECTRONIC APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-25 EP claimed
WO-2007146382-A2 HYDROPHOBIC COMPOSITIONS FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-21 WO claimed
US-20070290379-A1 Hydrophobic compositions for electronic applications E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-20 US claimed
US-20070083016-A1 Photosensitive polyimide compositions E. I. DUPONT DE NEMOURS AND COMPANY 2007-04-12 US claimed
US-20070083017-A1 Compositions comprising polyimide and hydrophobic epoxy, and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2007-04-12 US claimed
WO-2025100302-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING CURED RELIEF PATTERN USING SAME, AND SEMICONDUCTOR DEVICE 旭化成株式会社 2025-05-15 WO disclosed
US-20250138422-A1 PHOTOSENSITIVE RESIN COMPOSITION, MANUFACTURING METHOD OF ELECTRONIC DEVICE, AND ELECTRONIC DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2025-05-01 US disclosed
WO-2024204317-A1 RESIN COMPOSITION, FILM, FILM SET, OPTICAL WAVEGUIDE, PHOTOELECTRIC COMPOSITE SUBSTRATE, AND ELECTRONIC COMPONENT 住友ベークライト株式会社 2024-10-03 WO disclosed
WO-2024053564-A1 PHOTOSENSITIVE RESIN COMPOSITION, RESIN FILM, AND ELECTRONIC DEVICE 住友ベークライト株式会社 2024-03-14 WO disclosed
WO-2023190309-A1 SURFACE-MODIFIER RESIN COMPOSITION 住友ベークライト株式会社 2023-10-05 WO disclosed
WO-2023054381-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING ELECTRONIC DEVICE, ELECTRONIC DEVICE AND LIGHT DEVICE 住友ベークライト株式会社 2023-04-06 WO disclosed
WO-2007146383-A1 ORGANIC ENCAPSULANT COMPOSITIONS BASED ON HETEROCYCLIC POLYMERS FOR PROTECTION OF ELECTRONIC COMPONENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-21 WO disclosed
US-20070290379-A1 Hydrophobic compositions for electronic applications E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-20 US disclosed
US-20070291440-A1 Organic encapsulant compositions based on heterocyclic polymers for protection of electronic components E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-20 US disclosed
WO-2007047384-A1 COMPOSITIONS COMPRISING POLYIMIDE AND HYDROPHOBIC EPOXY, AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-26 WO disclosed
US-20070083016-A1 Photosensitive polyimide compositions E. I. DUPONT DE NEMOURS AND COMPANY 2007-04-12 US disclosed
US-20070083017-A1 Compositions comprising polyimide and hydrophobic epoxy, and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2007-04-12 US disclosed