Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 2/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329928 | 1.00 | CA4 (0.37) | CA4PGK1PGK2PEPDPGD | |
| SCHEMBL3473841 | 1.00 | CA4 (0.37) | CA4PGK1PGK2PEPDPGD | |
| SCHEMBL3473839 | 0.84 | MAPT (0.31) | — | |
| SCHEMBL17606430 | 0.84 | MMP1 (0.42) | CA4PEPDLAP3ALDH1A1MMP1 | |
| SCHEMBL16094426 | 0.84 | MAPT (0.31) | — | |
| SCHEMBL16093956 | 0.84 | BTN3A1 (0.35) | PGK1PGK2LPAR1LPAR3 | |
| SCHEMBL17423808 | 0.81 | CA4 (0.40) | CA4PGK1PGK2PEPDPGD | |
| SCHEMBL17281367 | 0.80 | CA4 (0.41) | CA4LAP3ALDH1A1 | |
| SCHEMBL16093955 | 0.80 | — | — | |
| SCHEMBL5789749 | 0.79 | CA4 (0.37) | CA4PGK1PGK2PGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220511-A1 | MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY FORMATE ASSIMILATION | GENOMATICA INC (US) | 2022-07-14 | — | — | US | claimed |
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | GENOMATICA, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20240294950-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | AGAIN BIO APS (DK) | 2024-09-05 | — | — | US | disclosed |
| EP-4421181-A2 | NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY | Genomatica, Inc. (US) | 2024-08-28 | — | — | EP | disclosed |
| EP-3741865-B1 | NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY | GENOMATICA INC (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-4296364-A2 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | Genomatica, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3967747-B1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | GENOMATICA INC (US) | 2023-11-08 | — | — | EP | disclosed |
| US-20230126921-A1 | NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY | AGAIN BIO APS (DK) | 2023-04-27 | — | — | US | disclosed |
| CN-110049760-B | Composition for treating inflammatory diseases, application thereof and probiotic composition | 链生物技术有限公司 | 2022-09-16 | — | — | CN | disclosed |
| US-20220220511-A1 | MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY FORMATE ASSIMILATION | GENOMATICA INC (US) | 2022-07-14 | — | — | US | disclosed |
| WO-2015084633-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | GENOMATICA, INC. (US) | 2015-06-11 | — | — | WO | disclosed |
| US-20150050708-A1 | MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY FORMATE ASSIMILATION | GENOMATICA, INC. (US) | 2015-02-19 | — | — | US | disclosed |
| WO-2014152434-A2 | MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY FORMATE ASSIMILATION | GENOMATICA, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| EP-2176415-B1 | PREPARING METHOD FOR (S)-3-HYDROXYBUTYRIC ACID AND (S)-3-HYDROXYBUTYRATE ESTER USING RECOMBINANT MICROORGANISM | LG CHEMICAL LTD (KR) | 2014-05-07 | — | — | EP | disclosed |
| CN-101802200-B | Preparing method for (s)-3-hydroxybutyric acid and (s)-3-hydroxybutyrate ester using recombinant microorganism | LG CHEMICAL LTD | 2013-11-20 | — | — | CN | disclosed |
| US-8535918-B2 | Preparing method for (S)-3hydroxybutyric acid and (S)-3 hydroxybutyrate ester using recombinant microorganism | LG CHEM, LTD. (KR) | 2013-09-17 | — | — | US | disclosed |
| US-20100209983-A1 | PREPARING METHOD FOR (S)-3HYDROXYBUTYRIC ACID AND (S)-3 HYDROXYBUTYRATE ESTER USING RECOMBINANT MICROORGANISM | LG-CHEM, LTD. (KR) | 2010-08-19 | — | — | US | disclosed |
| CN-101802200-A | Preparing method for (s)-3-hydroxybutyric acid and (s)-3-hydroxybutyrate ester using recombinant microorganism | LG CHEMICAL LTD | 2010-08-11 | — | — | CN | disclosed |
| EP-2176415-A1 | PREPARING METHOD FOR (S)-3-HYDROXYBUTYRIC ACID AND (S)-3-HYDROXYBUTYRATE ESTER USING RECOMBINANT MICROORGANISM | LG Chem. Ltd. (KR) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009020279-A1 | PREPARING METHOD FOR (S)-3-HYDROXYBUTYRIC ACID AND (S)-3-HYDROXYBUTYRATE ESTER USING RECOMBINANT MICROORGANISM | LG CHEM, LTD. (KR) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | ALDOA, FDPS, DERA | CA4 683/4885PGK1 415/4885PGK2 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.