SCHEMBL3474146

SCHEMBL3474146

Brc1cc(-n2c3ccccc3c3ccccc32)ccc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ ATM Q13315 1/20 0.50
▸ ALDH1A1 P00352 4/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.38
▸ HDAC4 P56524 1/20 0.38
▸ KMT2A Q03164 3/20 0.36
▸ IL1R1 P14778 1/20 0.36
▸ MAPT P10636 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ HTT P42858 1/20 0.35
▸ PTPN1 P18031 2/20 0.33
▸ MAPK14 Q16539 1/20 0.33
▸ EDNRB P24530 1/20 0.33
▸ EDNRA P25101 1/20 0.33
▸ HTR6 P50406 1/20 0.33
▸ HPGD P15428 2/20 0.32
▸ MPI P34949 1/20 0.32
▸ ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25921486 0.87 L3MBTL1 (0.50) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL30813010 0.85 KDM4E (0.47) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL65354 0.84 L3MBTL1 (0.55) L3MBTL1KDM4EATMALDH1A1HSD17B10
SCHEMBL21580226 0.84 L3MBTL1 (0.52) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL15806123 0.83 L3MBTL1 (0.51) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL17742520 0.83 KDM4E (0.46) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL17056616 0.82 L3MBTL1 (0.50) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL25222267 0.82 L3MBTL1 (0.42) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL17056800 0.82 ALDH1A1 (0.44) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL23154589 0.81 L3MBTL1 (0.52) L3MBTL1KDM4EATMALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7842406-B2 OLED device with substituted acridone compounds GLOBAL OLED TECHNOLOGY LLC (US) 2010-11-30 — — US disclosed
US-20090153030-A1 OLED DEVICE WITH SUBSTITUTED ACRIDONE COMPOUNDS GLOBAL OLED TECHNOLOGY LLC 2009-06-18 — — US disclosed
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