Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16125388 | 0.92 | KDM4E (0.57) | KDM4EATML3MBTL1HDAC4PTPN1 | |
| SCHEMBL29581819 | 0.90 | KDM4E (0.59) | KDM4EATML3MBTL1HDAC4PTPN1 | |
| SCHEMBL17742560 | 0.90 | KDM4E (0.59) | KDM4EATML3MBTL1HDAC4PTPN1 | |
| SCHEMBL347580 | 0.90 | KDM4E (0.59) | KDM4EATML3MBTL1HDAC4PTPN1 | |
| SCHEMBL4570440 | 0.86 | KDM4E (0.64) | KDM4EATML3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL13049621 | 0.86 | KDM4E (0.64) | KDM4EATML3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL29400116 | 0.84 | KDM4E (0.67) | KDM4EATML3MBTL1HDAC4PTPN1 | |
| SCHEMBL262160 | 0.84 | KDM4E (0.67) | KDM4EATML3MBTL1HDAC4PTPN1 | |
| SCHEMBL3904085 | 0.83 | KDM4E (0.65) | KDM4EATML3MBTL1PTPN1SCN9A | |
| SCHEMBL16890387 | 0.83 | KDM4E (0.52) | KDM4EATML3MBTL1HDAC4PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448925-B1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORP (JP) | 2017-12-06 | — | — | EP | disclosed |
| EP-2448925-B1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORP (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-8927121-B2 | Emissive aryl-heteroaryl compounds | NITTO DENKO CORPORATION (JP) | 2015-01-06 | — | — | US | disclosed |
| US-8927121-B2 | Emissive aryl-heteroaryl compounds | NITTO DENKO CORPORATION (JP) | 2015-01-06 | — | — | US | disclosed |
| US-8927121-B2 | Emissive aryl-heteroaryl compounds | NITTO DENKO CORPORATION (JP) | 2015-01-06 | — | — | US | disclosed |
| US-8771845-B2 | — | — | 2014-07-08 | — | — | US | disclosed |
| US-8771845-B2 | — | — | 2014-07-08 | — | — | US | disclosed |
| US-8771845-B2 | — | — | 2014-07-08 | — | — | US | disclosed |
| US-20130284907-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2013-10-31 | — | — | US | disclosed |
| US-20130284907-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2013-10-31 | — | — | US | disclosed |
| US-20120015998-A1 | PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20120015998-A1 | PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20120015998-A1 | PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
| WO-2012009283-A1 | PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012009283-A1 | PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-19 | — | — | WO | disclosed |
| WO-2011008560-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2011-01-20 | — | — | WO | disclosed |
| WO-2011008560-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2011-01-20 | — | — | WO | disclosed |
| US-20100326526-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20100326526-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20100326526-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015998-A1 | PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS | ARNT, AHR, AR | KDM4E 3036/4885ATM 1351/4885L3MBTL1 2273/4885 |
| US-20100326526-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | AHR, AR, ARNT | KDM4E 3441/4885ATM 2026/4885L3MBTL1 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.