SCHEMBL4570440

SCHEMBL4570440

c1ccc2c(c1)c1ccccc1n2-c1ccc(Oc2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
ATM Q13315 1/20 0.64
PTPN1 P18031 2/20 0.49
NTRK1 P04629 1/20 0.44
IGF1R P08069 1/20 0.44
FGFR1 P11362 1/20 0.44
NTRK3 Q16288 1/20 0.44
NTRK2 Q16620 1/20 0.44
SCN9A Q15858 4/20 0.44
MAPT P10636 4/20 0.43
LMNA P02545 1/20 0.43
MGLL Q99685 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LTA4H P09960 2/20 0.40
TSHR P16473 1/20 0.40
GPR3 P46089 1/20 0.39
PPARG P37231 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13049621 1.00 KDM4E (0.64) KDM4EL3MBTL1ATMPTPN1NTRK1
SCHEMBL3904085 0.96 KDM4E (0.65) KDM4EL3MBTL1ATMPTPN1NTRK1
SCHEMBL16125388 0.94 KDM4E (0.57) KDM4EL3MBTL1ATMPTPN1NTRK1
SCHEMBL13715283 0.91 LTA4H (0.53) KDM4EL3MBTL1ATMPTPN1NTRK1
SCHEMBL16890212 0.91 KDM4E (0.53) KDM4EL3MBTL1ATMPTPN1NTRK1
SCHEMBL13141903 0.89 KDM4E (0.52) KDM4EL3MBTL1ATMPTPN1NTRK1
SCHEMBL347441 0.86 KDM4E (0.48) KDM4EL3MBTL1ATMPTPN1NTRK1
SCHEMBL25904367 0.86 KDM4E (0.53) KDM4EL3MBTL1ATMPTPN1NTRK1
SCHEMBL77361 0.86 L3MBTL1 (0.84) KDM4EL3MBTL1ATMPTPN1MAPT
SCHEMBL29462713 0.86 L3MBTL1 (0.84) KDM4EL3MBTL1ATMPTPN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024147321-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2024-07-11 WO disclosed
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-07 US disclosed
US-20230048761-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed
WO-2022257817-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS 清华大学 2022-12-15 WO disclosed
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-15 US disclosed
US-20220037591-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-03 US disclosed
US-7371469-B2 Organic electroluminescent element, illuminator and display KONICA MINOLTA HOLDINGS, INC. (JP) 2008-05-13 US disclosed
US-7371469-B2 Organic electroluminescent element, illuminator and display KONICA MINOLTA HOLDINGS, INC. (JP) 2008-05-13 US disclosed
US-20070196687-A1 Organic Electroluminescence Element Material, Organic Electroluminescence Element,Display Device And Illumination Device KONICA MINOLTA HOLDING, INC. (JP) 2007-08-23 US disclosed
US-20070196687-A1 Organic Electroluminescence Element Material, Organic Electroluminescence Element,Display Device And Illumination Device KONICA MINOLTA HOLDING, INC. (JP) 2007-08-23 US disclosed
US-20070196690-A1 Organic electroluminescent element material, organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-23 US disclosed
US-20070196690-A1 Organic electroluminescent element material, organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-23 US disclosed
US-20070196691-A1 Organic electroluminescent element, white light emission element, full color display device and lighting device MERCK PATENT GMBH (DE) 2007-08-23 US disclosed
US-20070196691-A1 Organic electroluminescent element, white light emission element, full color display device and lighting device MERCK PATENT GMBH (DE) 2007-08-23 US disclosed
US-20070099025-A1 Organic electroluminescent element, illuminator and display KONICA MINOLTA HOLDINGS, INC. (JP) 2007-05-03 US disclosed
US-20070099025-A1 Organic electroluminescent element, illuminator and display KONICA MINOLTA HOLDINGS, INC. (JP) 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus TYR, AOC2, AOC1 KDM4E 2025/4885L3MBTL1 195/4885ATM 2251/4885
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 KDM4E 4253/4885L3MBTL1 1119/4885ATM 3272/4885
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device AOC2, TYR, BMI1 KDM4E 1959/4885L3MBTL1 283/4885ATM 2138/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 KDM4E 1340/4885L3MBTL1 679/4885ATM 3092/4885
US-20220037591-A1 Polycyclic aromatic compound F11, C1R, RNF31 KDM4E 4253/4885L3MBTL1 1119/4885ATM 3272/4885
US-20230048761-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE CCNE2, EMC2, CHRM2 KDM4E 2553/4885L3MBTL1 262/4885ATM 1268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.