Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22465830 | 0.83 | CA1 (0.50) | CA1CA2ALDH1A1TSHRTDP1 | |
| SCHEMBL1167202 | 0.81 | ALDH1A1 (0.44) | CA1CA2ALDH1A1TSHRTDP1 | |
| SCHEMBL2563835 | 0.81 | CA1 (0.51) | CA1CA2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL2006657 | 0.81 | ALDH1A1 (0.44) | CA1CA2ALDH1A1TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL28185221 | 0.79 | CA1 (0.50) | CA1CA2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL24462294 | 0.79 | ALDH1A1 (0.42) | CA1CA2ALDH1A1TSHRTDP1 | |
| SCHEMBL13826361 | 0.78 | CA1 (0.46) | CA1CA2ALDH1A1TSHRTDP1 | |
| SCHEMBL21101861 | 0.78 | CA1 (0.49) | CA1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL5515066 | 0.76 | CA1 (0.47) | CA1CA2TDP1NPC1RAB9A | |
| SCHEMBL183551 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256092-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| WO-2009140309-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | WO | disclosed |
| CN-101516837-A | Sulfonamide derivatives | HOFFMANN LA ROCHE (CH) | 2009-08-26 | — | — | CN | disclosed |
| US-4390476-A | Phosphonium compounds, a process for their preparation and a process for the preparation of asymmetrically substituted stilbene fluorescent brightening agents | CIBA-GEIGY CORPORATION (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0001991-B1 | PHOSPHONIUM COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PROCESS FOR THE PREPARATION OF OPTICAL BRIGHTENERS BASED ON ASYMMETRICALLY SUBSTITUTED STILBENES | CIBA-GEIGY AG (CH) | 1982-10-13 | — | — | EP | disclosed |
| US-4316860-A | FLUORESCENT BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1982-02-23 | — | — | US | disclosed |
| US-4231957-A | Phosphonium compounds, a process for their preparation and a process for the preparation of asymmetrically substituted stilbene fluorescent brightening agents | CIBA-GEIGY CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| EP-0001991-A1 | Phosphonium compounds, process for their preparation and process for the preparation of optical brighteners based on asymmetrically substituted stilbenes | CIBA-GEIGY AG (CH) | 1979-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256092-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, BTD | CA1 4452/4885CA2 1155/4885ALDH1A1 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.