SCHEMBL2563835

SCHEMBL2563835

CCc1ccc(S(=O)(=O)O)o1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.51
CA2 P00918 3/20 0.51
ALDH1A1 P00352 6/20 0.37
GAA P10253 2/20 0.37
MAPK1 P28482 1/20 0.37
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
ALOX5 P09917 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP1B1 Q16678 1/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28185221 0.98 CA1 (0.50) CA1CA2ALDH1A1GAAMAPK1
Pyridine SCHEMBL18007597 0.87 CA1 (0.49) CA1CA2ALDH1A1GAAMAPK1
SCHEMBL21101861 0.84 CA1 (0.49) CA1CA2ALDH1A1GAAMAPK1
SCHEMBL15483351 0.81 ALDH1A1 (0.35) CA1CA2ALDH1A1GAAMAPK1
SCHEMBL3474672 0.81 CA1 (0.53) CA1CA2ALDH1A1GAANPC1
SCHEMBL9424647 0.79 ALDH1A1 (0.44) CA1CA2ALDH1A1GAAMAPK1
SCHEMBL18007541 0.79 ALDH1A1 (0.34) CA1CA2ALDH1A1GAAMAPK1
SCHEMBL18843172 0.78 EPHX2 (0.48) CA1CA2ALDH1A1ALOX5PTGS1
SCHEMBL22465843 0.78 EPHX2 (0.48) CA1CA2ALDH1A1ALOX5PTGS1
SCHEMBL22465831 0.78 EPHX2 (0.48) CA1CA2ALDH1A1ALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11149188-B2 Oleofuransulfonate surfactants for use in wellbore applications HALLIBURTON ENERGY SERVICES, INC. (US) 2021-10-19 US claimed
US-20200308475-A1 OLEOFURANSULFONATE SURFACTANTS FOR USE IN WELLBORE APPLICATIONS HALLIBURTON ENERGY SERVICES, INC. 2020-10-01 US claimed
CN-113582889-B Sulfonylureas and related compounds and uses thereof 昆士兰大学 2024-09-20 CN disclosed
US-11845715-B2 2023-12-19 US disclosed
US-11845715-B2 2023-12-19 US disclosed
US-11149188-B2 Oleofuransulfonate surfactants for use in wellbore applications HALLIBURTON ENERGY SERVICES, INC. (US) 2021-10-19 US disclosed
US-11149188-B2 Oleofuransulfonate surfactants for use in wellbore applications HALLIBURTON ENERGY SERVICES, INC. (US) 2021-10-19 US disclosed
EP-3888749-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University of Queensland (AU) 2021-10-06 EP disclosed
US-11130731-B2 Sulfonylureas and related compounds and use of same THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2021-09-28 US disclosed
US-20200308475-A1 OLEOFURANSULFONATE SURFACTANTS FOR USE IN WELLBORE APPLICATIONS HALLIBURTON ENERGY SERVICES, INC. 2020-10-01 US disclosed
US-20200308475-A1 OLEOFURANSULFONATE SURFACTANTS FOR USE IN WELLBORE APPLICATIONS HALLIBURTON ENERGY SERVICES, INC. 2020-10-01 US disclosed
US-7834002-B2 4-amino-5-cyanopyrimidine derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-11-16 US disclosed
US-7834002-B2 4-amino-5-cyanopyrimidine derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-11-16 US disclosed
WO-2010085968-A1 TOLUIDINE SULFONAMIDES AND THEIR USE AS HIF-INHIBITORS EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) 2010-08-05 WO disclosed
WO-2010076034-A1 TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) 2010-07-08 WO disclosed
US-20080182854-A1 4-Amino-5-Cyanopyrimidine Derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-07-31 US disclosed
US-20080182854-A1 4-Amino-5-Cyanopyrimidine Derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-07-31 US disclosed
EP-1740574-B1 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES OTSUKA PHARMA CO LTD (JP) 2007-06-27 EP disclosed
US-4430355-A ARTIFICIAL SWEETENER DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-02-07 US disclosed
US-4233333-A 4,5-Dimethyl-thieno[3,2-d]isothiazolo-3(2H)-one-1,1-dioxides, compositions, and methods of use as a sweetener BOEHRINGER INGELHEIM GMBH (DE) 1980-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11845715-B2 NLRP3, PYCARD, NOD1 CA1 4541/4885CA2 3818/4885ALDH1A1 3407/4885
US-20080182854-A1 4-Amino-5-Cyanopyrimidine Derivatives ADORA2A, ADORA1, ADORA3 CA1 4672/4885CA2 755/4885ALDH1A1 381/4885
US-11130731-B2 Sulfonylureas and related compounds and use of same NLRP3, PYCARD, IAPP CA1 4141/4885CA2 2434/4885ALDH1A1 3558/4885
US-11149188-B2 Oleofuransulfonate surfactants for use in wellbore applications VAPB, OSBP, STOM CA1 2947/4885CA2 2895/4885ALDH1A1 4567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.