Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 6/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM6A | O15550 | 3/20 | 0.42 |
| ▸ | KDM5C | P41229 | 3/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.42 |
| ▸ | KDM6B | O15054 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4B | O94953 | 2/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.42 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.42 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476221 | 0.89 | SENP6 (0.41) | HDAC1SENP6SENP7HDAC6ACHE | |
| SCHEMBL3478373 | 0.89 | HDAC1 (0.42) | CYP2C19HDAC1SENP6SENP7HDAC6 | |
| SCHEMBL3475816 | 0.89 | HRH4 (0.46) | SENP6SENP7APAF1MAPTSMN1; SMN2 | |
| SCHEMBL3478593 | 0.85 | SENP6 (0.40) | HDAC1SENP6SENP7HDAC6ACHE | |
| SCHEMBL2773622 | 0.83 | HRH4 (0.44) | SENP6SENP7APAF1MAPTSMN1; SMN2 | |
| SCHEMBL2775160 | 0.82 | HRH4 (0.43) | SENP6SENP7APAF1MAPTSMN1; SMN2 | |
| SCHEMBL2772133 | 0.81 | HRH4 (0.42) | SENP6SENP7APAF1MAPTSMN1; SMN2 | |
| SCHEMBL3477066 | 0.80 | HRH4 (0.41) | SENP6SENP7APAF1MAPTSMN1; SMN2 | |
| SCHEMBL2775667 | 0.80 | SENP6 (0.41) | SENP6SENP7APAF1MAPTSMN1; SMN2 | |
| SCHEMBL3478113 | 0.80 | LMNA (0.41) | CYP2C19SENP6SENP7APAF1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130900-A2 | TRIAMINOPYRIMIDINE DERIVATIVES AS CDC25 PHOSPHATASE INHIBITORS | IPSEN PHARMA S.A.S. (FR) | 2010-11-18 | — | — | WO | claimed |
| WO-2010130900-A2 | TRIAMINOPYRIMIDINE DERIVATIVES AS CDC25 PHOSPHATASE INHIBITORS | IPSEN PHARMA S.A.S. (FR) | 2010-11-18 | — | — | WO | disclosed |