SENP6 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL61076	0.52	4/20
SCHEMBL61077	0.52	4/20
SCHEMBL66528	0.52	4/20
SCHEMBL12261	0.54	3/20
SCHEMBL59246	0.47	3/20
SCHEMBL36613	1.00	2/20
SCHEMBL107774	1.00	2/20
SCHEMBL108116	0.78	2/20
SCHEMBL66273	0.68	2/20
SCHEMBL108264	0.63	2/20
SCHEMBL97053	0.59	2/20
SCHEMBL35556	0.57	2/20
SCHEMBL74322	0.56	2/20
SCHEMBL91541	0.56	2/20
SCHEMBL91673	0.55	2/20
Benoxaprofen (SCHEMBL24413)	0.55	2/20
Benoxaprofen (SCHEMBL24414)	0.55	2/20
Dioxybenzone (SCHEMBL15894)	0.55	2/20
Chlorzoxazone (SCHEMBL35177)	0.54	2/20
SCHEMBL92080	0.54	2/20

Clinical trials — most relevant to SENP6 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Tumor Gene Expression in Women With Ovarian Cancer	PHASE4	COMPLETED
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit	PHASE2/PHASE3	WITHDRAWN
Bristol-Myers Squibb Dasatinib Src Inhibition in Endometrial Cancer	EARLY_PHASE1	COMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis	nan	UNKNOWN
Evaluation of Prognostic Factors: From Breast Cancer to Bone Metastases	nan	UNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Apoptosis Markers in Aggressive Periodontitis	nan	COMPLETED
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study	nan	COMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas	nan	RECRUITING
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure	nan	RECRUITING
Autophagy Bladder Cancer	nan	UNKNOWN
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma	nan	COMPLETED
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Circulating Markers for Ischemic Heart Disease	nan	RECRUITING
Expression and Clinical Significance of IGHD in Pancreatic Cancer	nan	UNKNOWN
Exosome-based Liquid Biopsies for Upper Gastrointestinal Cancers Diagnosis	nan	UNKNOWN
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men	nan	RECRUITING
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia	nan	UNKNOWN
Analysis of the Variation in Caspase-8 Availability and Cleavage in Oral Squamous Cell Carcinoma	nan	UNKNOWN
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)	nan	COMPLETED
The Significance of Urine UbA52 In the Diagnosis of Diabetic Nephropathy	nan	COMPLETED
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis	nan	COMPLETED
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s)	nan	COMPLETED
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors	nan	NOT_YET_RECRUITING
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Long Term Prediction of MASH-related HCC Risk by Proteomics	nan	NOT_YET_RECRUITING
The Influence of Secretin Stimulated Pancreatic Secretion on ctDNA Expression in Patients With Pancreatic Ductal Adenocarcinoma: The Role of Biomarkers in Determining the Prognosis of Pancreatic Ductal Adenocarcinoma	nan	NOT_YET_RECRUITING
Cardiac Injury in COVID-19: a Pathology Study	nan	UNKNOWN
Identification of New FTLD Genes	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a SENP6 binder may also engage these)

Protein	Name	Similarity
Q6P7W0	—	0.998	Q6P7W0 →
Q7Z353	—	0.987	Q7Z353 →
A7MBJ2	—	0.986	A7MBJ2 →
Q80Y19	—	0.986	Q80Y19 →
Q99ME3	—	0.986	Q99ME3 →
Q6P4F7	—	0.986	Q6P4F7 →
Q6GNV6	—	0.985	Q6GNV6 →
Q0VEE6	—	0.985	Q0VEE6 →
Q9DAU9	—	0.985	Q9DAU9 →
SENP7	Sentrin-specific protease 7	0.985	landscape →
Q8IZM8	—	0.984	Q8IZM8 →
A8MW92	—	0.984	A8MW92 →
Q14865	—	0.984	Q14865 →
Q6ZV73	—	0.984	Q6ZV73 →
Q80XJ2	—	0.984	Q80XJ2 →
Q6GPJ8	—	0.984	Q6GPJ8 →
Q0IIM1	—	0.984	Q0IIM1 →
HIPK3	Homeodomain-interacting protein kinase 3	0.984	landscape →
Q5VYS8	—	0.984	Q5VYS8 →
Q99708	—	0.983	Q99708 →
Q5W4S4	—	0.983	Q5W4S4 →
Q96T21	—	0.983	Q96T21 →
Q8WZ64	—	0.983	Q8WZ64 →
P62292	—	0.983	P62292 →
Q8CCH7	—	0.983	Q8CCH7 →
F1N5V1	—	0.983	F1N5V1 →
D3ZF42	—	0.982	D3ZF42 →
Q8BM75	—	0.982	Q8BM75 →
Q8BUH8	—	0.982	Q8BUH8 →
Q4V9H5	—	0.982	Q4V9H5 →