Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3474884 | 0.93 | TSHR (0.39) | TSHRDNM1 | |
| SCHEMBL6050145 | 0.91 | TSHR (0.37) | TSHRDNM1 | |
| SCHEMBL3429100 | 0.88 | — | — | |
| SCHEMBL3677002 | 0.87 | TSHR (0.50) | TSHRDNM1ALDH1A1TDP1 | |
| SCHEMBL6050201 | 0.86 | TSHR (0.37) | TSHRDNM1 | |
| SCHEMBL3427139 | 0.83 | — | — | |
| SCHEMBL10155552 | 0.82 | TSHR (0.46) | TSHRDNM1 | |
| SCHEMBL3673710 | 0.82 | TSHR (0.46) | TSHRDNM1ALDH1A1TDP1 | |
| SCHEMBL29102703 | 0.82 | TSHR (0.37) | TSHRDNM1 | |
| SCHEMBL6050196 | 0.82 | TSHR (0.37) | TSHRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790897-B2 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090144915-A1 | Graftable hindered amine light stabilizers | MEIER HANS-RUDOLF | 2009-06-11 | — | — | US | disclosed |
| US-7504510-B2 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-03-17 | — | — | US | disclosed |
| EP-1084710-B1 | ADENOSINE A1 ANTAGONISTS FOR MALE STERILITY | ASTELLAS PHARMA INC (JP) | 2006-10-18 | — | — | EP | disclosed |
| EP-1592664-B1 | GRAFTABLE HINDERED AMINE LIGHT STABILIZERS | CIBA SC HOLDING AG (CH) | 2006-08-23 | — | — | EP | disclosed |
| US-20060173107-A1 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. | 2006-08-03 | — | — | US | disclosed |
| EP-1592664-A1 | GRAFTABLE HINDERED AMINE LIGHT STABILIZERS | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072035-A1 | GRAFTABLE HINDERED AMINE LIGHT STABILIZERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-26 | — | — | WO | disclosed |
| US-20040152659-A1 | Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| US-6521656-B1 | Contacting sperm with a pyrazolo(1,5-a)pyridine acrosomal reaction induction promoter then joining with ovum | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-02-18 | — | — | US | disclosed |
| WO-1993025205-A1 | PYRAZOLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF ANEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-12-23 | — | — | WO | disclosed |
| US-5204346-A | Cognition activators; analgesics; antidepressants; vasodilation; cardiovascular and urogential disorders; | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-20 | — | — | US | disclosed |
| EP-0497258-A2 | Use of adenosine antagonists in the prevention and treatment of pancreatitis and ulcer | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |
| EP-0467248-A2 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0003002-B1 | USE OF AROMATIC-ALIPHATIC KETONES AS PHOTOINITIATORS, PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH KETONES AND AROMATIC-ALIPHATIC KETONES | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | disclosed |
| US-4321118-A | Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition | CIBA-GEIGY CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4318791-A | PHOTOPOLYMERIZABLE SYSTEM FOR INKS | CIBA-GEIGY CORPORATION (US) | 1982-03-09 | — | — | US | disclosed |
| US-4315807-A | Sensitizers for photopolymerization | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| US-4308400-A | AROMATIC HYDROXY KETONES | CIBA-GEIGY A.G. (CH) | 1981-12-29 | — | — | US | disclosed |
| EP-0003002-A2 | Use of aromatic-aliphatic ketones as photoinitiators, photopolymerisable systems containing such ketones and aromatic-aliphatic ketones | CIBA-GEIGY AG (CH) | 1979-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152659-A1 | Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist | ADORA2A, ADORA1, ADORA2B | TSHR 601/4885DNM1 1124/4885ALDH1A1 336/4885 |
| US-20090144915-A1 | Graftable hindered amine light stabilizers | IDO1, MAOA, AOX1 | TSHR 3638/4885DNM1 2028/4885ALDH1A1 29/4885 |
| US-20060173107-A1 | Graftable hindered amine light stabilizers | IDO1, MAOA, TPH1 | TSHR 3853/4885DNM1 1641/4885ALDH1A1 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.