Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530603 | 0.81 | TDP1 (0.59) | TDP1ALDH1A1KEAP1KMT2AMEN1 | |
| SCHEMBL7817852 | 0.80 | TDP1 (0.61) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| SCHEMBL27726024 | 0.79 | TDP1 (0.56) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| SCHEMBL3473789 | 0.77 | TDP1 (0.54) | TDP1ALDH1A1KEAP1KMT2AMEN1 | |
| SCHEMBL7610731 | 0.76 | TDP1 (0.53) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| SCHEMBL3183513 | 0.76 | TSHR (0.68) | TDP1ALDH1A1KEAP1KMT2AMEN1 | |
| SCHEMBL11207011 | 0.75 | TDP1 (0.51) | TDP1ALDH1A1KEAP1KMT2AFFAR1 | |
| SCHEMBL27540219 | 0.75 | TSHR (0.66) | TDP1ALDH1A1KEAP1KMT2AMEN1 | |
| SCHEMBL27726053 | 0.74 | TDP1 (0.54) | TDP1ALDH1A1KEAP1KMT2AMEN1 | |
| SCHEMBL3185725 | 0.73 | TDP1 (0.68) | TDP1ALDH1A1KEAP1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318960-B2 | Diarylphosphine- and dialkylphosphine-containing compounds, processes of preparing same and uses thereof as tridentate ligands | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2012-11-27 | — | — | US | disclosed |
| US-20100292084-A1 | NOVEL DIARYLPHOSPHINE- AND DIALKYLPHOSPHINE-CONTAINING COMPOUNDS, PROCESSES OF PREPARING SAME AND USES THEREOF AS TRIDENTATE LIGANDS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292084-A1 | NOVEL DIARYLPHOSPHINE- AND DIALKYLPHOSPHINE-CONTAINING COMPOUNDS, PROCESSES OF PREPARING SAME AND USES THEREOF AS TRIDENTATE LIGANDS | MVD, DDT, AGPS | TDP1 624/4885ALDH1A1 2141/4885KEAP1 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.