Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780729 | 0.89 | HDAC1 (0.56) | TDP1KMT2AHDAC2HDAC8HDAC6 | |
| SCHEMBL28530603 | 0.84 | TDP1 (0.59) | TDP1KEAP1ALDH1A1FFAR1KMT2A | |
| SCHEMBL27726033 | 0.82 | TDP1 (0.53) | TDP1KEAP1ALDH1A1FFAR1KMT2A | |
| SCHEMBL27735059 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KMT2AHDAC8HDAC6TSHR | |
| SCHEMBL27726024 | 0.81 | TDP1 (0.56) | TDP1KEAP1ALDH1A1FFAR1KMT2A | |
| SCHEMBL3475314 | 0.80 | TDP1 (0.54) | TDP1KEAP1ALDH1A1FFAR1KMT2A | |
| SCHEMBL3473789 | 0.80 | TDP1 (0.54) | TDP1KEAP1ALDH1A1FFAR1KMT2A | |
| SCHEMBL27726053 | 0.80 | TDP1 (0.54) | TDP1KEAP1ALDH1A1FFAR1KMT2A | |
| SCHEMBL7610731 | 0.78 | TDP1 (0.53) | TDP1KEAP1ALDH1A1FFAR1KMT2A | |
| SCHEMBL8656330 | 0.78 | LAP3 (0.44) | HDAC2HDAC8HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114197222-A | Flame-retardant anti-dripping polyester fiber and preparation method and application thereof | 山东龙港硅业科技有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-101205268-B | Method for hydrogenating conjugated diene polymer and hydrogenation catalyst composition | TSRC CORP | 2010-09-29 | — | — | CN | disclosed |
| CN-101205268-A | Method for hydrogenating conjugated diene polymer and hydrogenation catalyst composition | TSRC CORP (CN) | 2008-06-25 | — | — | CN | disclosed |
| EP-1064289-A1 | HETEROCYCLIC SIGNAL TRANSDUCTION INHIBITORS, COMPOSITIONS CONTAINING THEM | ARIAD PHARMACEUTICALS, INC. (US) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999047529-A1 | HETEROCYCLIC SIGNAL TRANSDUCTION INHIBITORS, COMPOSITIONS CONTAINING THEM | ARIAD PHARMACEUTICALS, INC. (US) | 1999-09-23 | — | — | WO | disclosed |