Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27560571 | 0.83 | TSHR (0.50) | ALDH1A1KMT2AL3MBTL1KDM4ELMNA | |
| SCHEMBL7817852 | 0.80 | TDP1 (0.61) | TDP1ALDH1A1KEAP1KMT2AHTT | |
| SCHEMBL27726024 | 0.79 | TDP1 (0.56) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL28530603 | 0.78 | TDP1 (0.59) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL3475314 | 0.77 | TDP1 (0.54) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL7610731 | 0.76 | TDP1 (0.53) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL1380801 | 0.76 | TDP1 (0.61) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL11207011 | 0.75 | TDP1 (0.51) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL27726053 | 0.74 | TDP1 (0.54) | TDP1ALDH1A1KEAP1KMT2AMEN1 | |
| SCHEMBL8772358 | 0.73 | TDP1 (0.58) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318960-B2 | Diarylphosphine- and dialkylphosphine-containing compounds, processes of preparing same and uses thereof as tridentate ligands | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2012-11-27 | — | — | US | disclosed |
| US-20100292084-A1 | NOVEL DIARYLPHOSPHINE- AND DIALKYLPHOSPHINE-CONTAINING COMPOUNDS, PROCESSES OF PREPARING SAME AND USES THEREOF AS TRIDENTATE LIGANDS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292084-A1 | NOVEL DIARYLPHOSPHINE- AND DIALKYLPHOSPHINE-CONTAINING COMPOUNDS, PROCESSES OF PREPARING SAME AND USES THEREOF AS TRIDENTATE LIGANDS | MVD, DDT, AGPS | TDP1 624/4885ALDH1A1 2141/4885KEAP1 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.