SCHEMBL3475665

SCHEMBL3475665

CCCCCCCCNc1ccccc1C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 6/20 0.66
HPGD P15428 2/20 0.61
ALDH1A1 P00352 1/20 0.61
HSD17B10 Q99714 1/20 0.61
CNR2 P34972 4/20 0.57
CYP2C9 P11712 1/20 0.57
KDM6B O15054 1/20 0.56
KDM4C Q9H3R0 1/20 0.56
PLK3 Q9H4B4 3/20 0.56
CA12 O43570 1/20 0.55
CA9 Q16790 1/20 0.55
MAPK8 P45983 1/20 0.54
CNR1 P21554 1/20 0.52
NAAA Q02083 2/20 0.51
KDM4E B2RXH2 1/20 0.51
AGTR1 P30556 1/20 0.51
RAB9A P51151 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30012239 1.00 PLK1 (0.66) PLK1HPGDALDH1A1HSD17B10CNR2
SCHEMBL10475728 1.00 PLK1 (0.66) PLK1HPGDALDH1A1HSD17B10CNR2
SCHEMBL11437269 1.00 PLK1 (0.66) PLK1HPGDALDH1A1HSD17B10CNR2
SCHEMBL11483067 1.00 PLK1 (0.66) PLK1HPGDALDH1A1HSD17B10CNR2
SCHEMBL5694119 1.00 PLK1 (0.66) PLK1HPGDALDH1A1HSD17B10CNR2
SCHEMBL11443814 1.00 PLK1 (0.66) PLK1HPGDALDH1A1HSD17B10CNR2
SCHEMBL11430175 1.00 PLK1 (0.66) PLK1HPGDALDH1A1HSD17B10CNR2
SCHEMBL11432358 1.00 PLK1 (0.66) PLK1HPGDALDH1A1HSD17B10CNR2
SCHEMBL5272720 1.00 PLK1 (0.66) PLK1HPGDALDH1A1HSD17B10CNR2
SCHEMBL27153029 1.00 PLK1 (0.66) PLK1HPGDALDH1A1HSD17B10CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110313158-A1 Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-12-22 US claimed
WO-2010097815-A2 A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-09-02 WO claimed
CN-110437162-B Compound containing cyclohydroximic acid and preparation method and application thereof 贵州医科大学 2021-01-05 CN disclosed
CN-110437162-A A kind of compound of the hydroximic acid containing ring and its preparation method and application UNIV GUIZHOU MEDICAL 2019-11-12 CN disclosed
US-20110313158-A1 Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-12-22 US disclosed
WO-2010097815-A2 A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-09-02 WO disclosed
EP-0815871-B1 Tape plaster comprising anthranilic acid derivatives as percutaneous absorption promotors LINTEC CORP (JP) 2002-07-17 EP disclosed
US-RE36138-E AMINO ACID DERIVATIVE; DRUG DELIVERY LINTEC CORPORATION (JP) 1999-03-09 US disclosed
EP-0815871-A1 A percutaneous absorption, a tape plaster and a method of promoting percutaneous absorption LINTEC Corporation (JP) 1998-01-07 EP disclosed
US-5413794-A Drug delivery LINTEC CORPORATION (JP) 1995-05-09 US disclosed
EP-0552405-A1 A percutaneous absorption promoter, a tape plaster and a method of promoting percutaneous absorption LINTEC Corporation (JP) 1993-07-28 EP disclosed
US-4212674-A N-OLEYL-1,3-PROPANEDIAMMONIUM DIOLEATE AND/OR DERIVATIVES AND A PARTICULATE CARRIER PLUSS-STAUFER AG (CH) 1980-07-15 US disclosed
US-4021470-A LUBRICANT STABILIZERS MOBIL OIL CORPORATION (US) 1977-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313158-A1 Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines HCN2, RAC2, HCN1 PLK1 2827/4885HPGD 2141/4885ALDH1A1 1225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.