Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8851020 | 0.94 | CYP1A2 (0.53) | CYP1A2LTA4HPAOXALDH1A1DGKA | |
| Hydrochloric Acid SCHEMBL10758938 | 0.92 | CYP1A2 (0.52) | CYP1A2LTA4HPAOXALDH1A1DGKA | |
| SCHEMBL31442225 | 0.92 | CYP1A2 (0.55) | CYP1A2LTA4HALDH1A1DGKAGAA | |
| SCHEMBL28674541 | 0.92 | CYP1A2 (0.55) | CYP1A2LTA4HALDH1A1DGKAGAA | |
| SCHEMBL16948556 | 0.90 | CYP1A2 (0.53) | CYP1A2LTA4HALDH1A1DGKAGAA | |
| SCHEMBL7518611 | 0.89 | DGKA (0.57) | CYP1A2LTA4HALDH1A1DGKAGAA | |
| SCHEMBL8636181 | 0.88 | CYP1A2 (0.59) | CYP1A2LTA4HALDH1A1GAAMGAM | |
| SCHEMBL8851605 | 0.86 | GAA (0.52) | CYP1A2LTA4HPAOXALDH1A1GAA | |
| SCHEMBL132536 | 0.85 | CYP1A2 (0.52) | CYP1A2LTA4HALDH1A1DGKAGAA | |
| SCHEMBL130596 | 0.85 | CYP1A2 (0.52) | CYP1A2LTA4HALDH1A1DGKAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101134-A1 | 5-MEMBERED HETEROARYL DERIVATIVES USED AS SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101134-A1 | 5-MEMBERED HETEROARYL DERIVATIVES USED AS SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONISTS | S1PR1, S1PR5, S1PR3 | CYP1A2 2262/4885LTA4H 703/4885PAOX 793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.