SCHEMBL347583

SCHEMBL347583

Cc1ccc(N(c2ccc(C)cc2)c2ccc(O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.68
ALDH1A1 P00352 5/20 0.48
TSHR P16473 2/20 0.48
ESR2 Q92731 4/20 0.43
MAPT P10636 6/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
KDM4E B2RXH2 3/20 0.42
ALOX15 P16050 3/20 0.42
HSD17B10 Q99714 3/20 0.42
RAB9A P51151 3/20 0.42
HPGD P15428 2/20 0.42
BLM P54132 2/20 0.42
CA2 P00918 2/20 0.42
NPC1 O15118 2/20 0.42
LMNA P02545 2/20 0.42
CYP3A4 P08684 2/20 0.42
HIF1A Q16665 2/20 0.42
CA12 O43570 1/20 0.42
GMNN O75496 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3743294 1.00 ACHE (0.68) ACHEALDH1A1TSHRESR2MAPT
SCHEMBL28032007 1.00 ACHE (0.68) ACHEALDH1A1TSHRESR2MAPT
SCHEMBL1378394 0.93 ACHE (0.59) ACHEALDH1A1TSHRESR2MAPT
SCHEMBL3737108 0.93 ACHE (0.59) ACHEALDH1A1TSHRESR2MAPT
SCHEMBL14173656 0.93 ACHE (0.59) ACHEALDH1A1TSHRESR2MAPT
SCHEMBL12144279 0.93 ACHE (0.59) ACHEALDH1A1TSHRESR2MAPT
SCHEMBL2609817 0.93 ACHE (0.59) ACHEALDH1A1TSHRESR2MAPT
SCHEMBL14173661 0.93 ACHE (0.59) ACHEALDH1A1TSHRESR2MAPT
SCHEMBL8178201 0.91 ACHE (0.56) ACHEALDH1A1TSHRESR2MAPT
Phenol SCHEMBL11507438 0.88 ACHE (0.52) ACHEALDH1A1TSHRMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7833684-B2 Triaryl amines such as N,N'-diphenyl-N,N'-bis(3-hydroxyphenyl) [1,1'-biphenyl]-4, 4'-diamineas charge control agents imparting excellent triboelectric charging characteristics to a toner particle comprising a latex, a pigment, and an optional wax; emulsion aggregation toners; xerography; resolution XEROX CORPORATION (US) 2010-11-16 US claimed
US-20090123860-A1 Triaryl amines such as N,N'-diphenyl-N,N'-bis(3-hydroxyphenyl) [1,1'-biphenyl]-4, 4'-diamineas charge control agents imparting excellent triboelectric charging characteristics to a toner particle comprising a latex, a pigment, and an optional wax; emulsion aggregation toners; xerography; resolution XEROX CORPORATION 2009-05-14 US claimed
EP-3843168-B1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE UNIV KYUSHU NAT UNIV CORP (JP) 2023-10-11 EP disclosed
US-20220119590-A1 POLYMERS WITH AMINE-GROUP-CONTAINING REPEATING UNITS MERCK PATENT GMBH (DE) 2022-04-21 US disclosed
US-20210277176-A1 FORMULATION CONTAINING A HIGHLY BRANCHED POLYMER, HIGHLY BRANCHED POLYMER AND ELECTRO-OPTICAL DEVICE CONTAINING THIS HIGHLY BRANCHED POLYMER MERCK PATENT GMBH (DE) 2021-09-09 US disclosed
EP-3843168-A1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE Kyushu University, National University Corporation (JP) 2021-06-30 EP disclosed
US-10862038-B2 Compositions comprising at least one polymer and at least one salt, and electroluminescent devices containing said compositions MERCK PATENT GMBH (DE) 2020-12-08 US disclosed
US-10651388-B2 Compositions comprising at least one polymer and at least one metal complex and to electroluminescent devices containing said compositions MERCK PATENT GMBH (DE) 2020-05-12 US disclosed
US-20170365786-A1 COMPOSITIONS COMPRISING AT LEAST ONE POLYMER AND AT LEAST ONE METAL COMPLEX AND TO ELECTROLUMINESCENT DEVICES CONTAINING SAID COMPOSITIONS MERCK PATENT GMBH (DE) 2017-12-21 US disclosed
US-20170365785-A1 COMPOSITIONS COMPRISING AT LEAST ONE POLYMER AND AT LEAST ONE SALT, AND ELECTROLUMINESCENT DEVICES CONTAINING SAID COMPOSITIONS MERCK PATENT GMBH (DE) 2017-12-21 US disclosed
EP-2448925-B1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORP (JP) 2017-12-06 EP disclosed
WO-2011008560-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2011-01-20 WO disclosed
US-20100326526-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2010-12-30 US disclosed
US-20100326526-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2010-12-30 US disclosed
US-20100326526-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2010-12-30 US disclosed
US-7833684-B2 Triaryl amines such as N,N'-diphenyl-N,N'-bis(3-hydroxyphenyl) [1,1'-biphenyl]-4, 4'-diamineas charge control agents imparting excellent triboelectric charging characteristics to a toner particle comprising a latex, a pigment, and an optional wax; emulsion aggregation toners; xerography; resolution XEROX CORPORATION (US) 2010-11-16 US disclosed
US-20090123860-A1 Triaryl amines such as N,N'-diphenyl-N,N'-bis(3-hydroxyphenyl) [1,1'-biphenyl]-4, 4'-diamineas charge control agents imparting excellent triboelectric charging characteristics to a toner particle comprising a latex, a pigment, and an optional wax; emulsion aggregation toners; xerography; resolution XEROX CORPORATION 2009-05-14 US disclosed
WO-2009053346-A1 USE OF DIPHENYLAMINO-BIS(PHENOXY)- AND BIS(DIPHENYLAMINO)-PHENOXYTRIAZINE COMPOUNDS BASF SE (DE) 2009-04-30 WO disclosed
US-6103436-A A PHOTOCONDUCTIVE LAYER COMPRISING A HYDROXY FUNCTIONALIZED AROMATIC DIAMINE AND A HYDROXY FUNCTIONALIZED TRIARYLAMINE AND A CROSSLINKED POLYAMIDE MATRIX XEROX CORPORATION (US) 2000-08-15 US disclosed
US-6099996-A FIRST CHARGE TRANSPORTING LAYER CONSISTS OF AROMATIC AMINE AND SECOND CHARGE TRANSPORTING LAYER CONTAINING AROMATIC AMINE WITH ARYLESTER GROUP XEROX CORPORATION (US) 2000-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100326526-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS AHR, AR, ARNT ACHE 1104/4885ALDH1A1 189/4885TSHR 1831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.