Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 18/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31339740 | 0.83 | GRM2 (0.57) | GRM2 | |
| SCHEMBL25429341 | 0.83 | GRM2 (0.57) | GRM2 | |
| SCHEMBL1993936 | 0.82 | GRM2 (0.39) | GRM2 | |
| SCHEMBL7811309 | 0.82 | GRM2 (0.39) | GRM2 | |
| SCHEMBL7819300 | 0.81 | GRM2 (0.39) | GRM2 | |
| SCHEMBL8513360 | 0.79 | GRM2 (0.40) | GRM2 | |
| SCHEMBL3474766 | 0.77 | GRM2 (0.39) | GRM2 | |
| SCHEMBL8512873 | 0.77 | GRM2 (0.42) | GRM2 | |
| SCHEMBL7810660 | 0.77 | GRM2 (0.39) | GRM2 | |
| SCHEMBL7879334 | 0.76 | GRM2 (0.34) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2705024-B1 | Alkyne benzotriazole derivatives | MERCK SHARP & DOHME (US) | 2015-12-16 | — | — | EP | disclosed |
| EP-2705024-B1 | Alkyne benzotriazole derivatives | MERCK SHARP & DOHME (US) | 2015-12-16 | — | — | EP | disclosed |
| US-9139576-B2 | Aminomethyl biaryl benzotriazole derivatives | MERCK SHARP & DOHME CORP. (US) | 2015-09-22 | — | — | US | disclosed |
| US-9139576-B2 | Aminomethyl biaryl benzotriazole derivatives | MERCK SHARP & DOHME CORP. (US) | 2015-09-22 | — | — | US | disclosed |
| US-9139576-B2 | Aminomethyl biaryl benzotriazole derivatives | MERCK SHARP & DOHME CORP. (US) | 2015-09-22 | — | — | US | disclosed |
| US-8785482-B2 | Cyclohexene benzotriazole derivatives | MERCK SHARP & DOHME CORP. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785482-B2 | Cyclohexene benzotriazole derivatives | MERCK SHARP & DOHME CORP. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785482-B2 | Cyclohexene benzotriazole derivatives | MERCK SHARP & DOHME CORP. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8772276-B2 | Alkyne benzotriazole derivatives | MERCK SHARP & DOHME CORP. (US) | 2014-07-08 | — | — | US | disclosed |
| US-8772276-B2 | Alkyne benzotriazole derivatives | MERCK SHARP & DOHME CORP. (US) | 2014-07-08 | — | — | US | disclosed |
| WO-2012151139-A1 | ALKYNE BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012151139-A1 | ALKYNE BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012151138-A1 | CYCLOHEXENE BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012151138-A1 | CYCLOHEXENE BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012151136-A1 | AMINOMETHYL BIARYL BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012151136-A1 | AMINOMETHYL BIARYL BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-11-08 | — | — | WO | disclosed |
| WO-2010141360-A1 | BIARYL BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010141360-A1 | BIARYL BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010114726-A1 | AMINOBENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010114726-A1 | AMINOBENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-10-07 | — | — | WO | disclosed |