Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RARB | P10826 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27904058 | 0.94 | KMT2A (0.55) | CSNK2A2CSNK2A1TP53TSHRPLA2G4B | |
| SCHEMBL3478444 | 0.88 | ACHE (0.49) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28969034 | 0.87 | NPC1 (0.63) | TP53TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28105060 | 0.87 | NPC1 (0.63) | TP53TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27621693 | 0.87 | NPC1 (0.63) | TP53TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29106946 | 0.87 | NPC1 (0.63) | TP53TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28969065 | 0.87 | NPC1 (0.63) | TP53TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8773507 | 0.87 | NPC1 (0.63) | TP53TSHRNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3478476 | 0.86 | ACHE (0.48) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5803249 | 0.85 | NPC1 (0.62) | TP53TSHRNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267779-A1 | Novel Compounds and Methods of Using Them | SYNDAX PHARMACEUTICALS, INC. (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267779-A1 | Novel Compounds and Methods of Using Them | HDAC1, HDAC3, HDAC6 | CSNK2A2 174/4885CSNK2A1 161/4885TP53 1472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.