SCHEMBL3476173

SCHEMBL3476173

Cn1ncc2cc(-c3ccc4oc(N5Cc6ccccc6C5)nc4c3)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 18/20 1.00
USP30 Q70CQ3 1/20 0.49
HDAC6 Q9UBN7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3474858 0.83 FAAH (1.00) FAAH
SCHEMBL3477942 0.83 FAAH (1.00) FAAHHDAC6
SCHEMBL3477852 0.78 FAAH (1.00) FAAH
SCHEMBL3476996 0.77 FAAH (1.00) FAAHHDAC6
SCHEMBL13436706 0.77 FAAH (0.78) FAAH
SCHEMBL13436710 0.75 FAAH (1.00) FAAHHDAC6
SCHEMBL3478207 0.74 FAAH (1.00) FAAH
SCHEMBL3476647 0.74 FAAH (0.69) FAAHHDAC6
SCHEMBL13436780 0.74 FAAH (1.00) FAAHHDAC6
SCHEMBL13436711 0.74 FAAH (1.00) FAAHHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed