SCHEMBL3477852

SCHEMBL3477852

CCn1ccc2cc(-c3ccc4oc(N5Cc6ccccc6C5)nc4c3)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13436706 0.88 FAAH (0.78) FAAH
SCHEMBL3474858 0.86 FAAH (1.00) FAAH
SCHEMBL3478069 0.85 FAAH (0.74) FAAH
SCHEMBL3476996 0.79 FAAH (1.00) FAAH
SCHEMBL3476647 0.79 FAAH (0.69) FAAH
SCHEMBL3476173 0.78 FAAH (1.00) FAAH
SCHEMBL3477838 0.76 FAAH (1.00) FAAH
SCHEMBL13436710 0.76 FAAH (1.00) FAAH
SCHEMBL3477451 0.75 FAAH (1.00) FAAH
SCHEMBL3478480 0.75 FAAH (0.90) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed