SCHEMBL347618

SCHEMBL347618

C1CN(COCN2CCOCC2)CCO1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.44
KDM4E B2RXH2 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
ALDH1A1 P00352 2/20 0.42
KEAP1 Q14145 1/20 0.42
HSD17B10 Q99714 3/20 0.41
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
ALOX15 P16050 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TSHR P16473 1/20 0.39
GLA P06280 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
CYP2C9 P11712 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CXCR4 P61073 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL347311 0.89 USP2 (0.41) USP2KDM4ESMN1; SMN2ALDH1A1KEAP1
Hydrogen Sulfide SCHEMBL17888866 0.87 USP2 (0.39) USP2KDM4ESMN1; SMN2ALDH1A1KEAP1
SCHEMBL6690289 0.85 KDM4E (0.46) USP2KDM4ESMN1; SMN2ALDH1A1KEAP1
SCHEMBL3305232 0.85 TSHR (0.41) USP2KDM4ESMN1; SMN2ALDH1A1KEAP1
SCHEMBL6690287 0.85 KDM4E (0.40) USP2KDM4ESMN1; SMN2ALDH1A1KEAP1
SCHEMBL6693136 0.81 KDM4E (0.38) USP2KDM4ESMN1; SMN2ALDH1A1KEAP1
SCHEMBL6693141 0.81 POLB (0.58) USP2KDM4ESMN1; SMN2ALDH1A1KEAP1
SCHEMBL21148004 0.81 SMN1; SMN2 (0.38) USP2KDM4ESMN1; SMN2ALDH1A1KEAP1
SCHEMBL3304899 0.81 ALDH1A1 (0.43) USP2KDM4ESMN1; SMN2ALDH1A1KEAP1
SCHEMBL26920081 0.79 TDP1 (0.44) USP2SMN1; SMN2ALDH1A1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119425311-A Purification method for efficiently removing degradation products of desthioamine liquid 河北精致科技有限公司 2025-02-14 CN claimed
CN-118236841-A Purifying method of flue gas absorbent 河北精致科技有限公司 2024-06-25 CN claimed
CN-115991528-A Method for purifying flue gas absorbent 河北精致科技有限公司 2023-04-21 CN claimed
CN-112262166-B Polyurethane foam-forming composition 速的奥公司 2023-04-04 CN claimed
WO-2022260859-A1 HCFO-CONTAINING ISOCYANATE-REACTIVE COMPOSITIONS, RELATED FOAM-FORMING COMPOSITIONS AND FLAME RETARDANT PUR-PIR FOAMS COVESTRO LLC (US) 2022-12-15 WO claimed
CN-114159946-B Absorbent for removing sulfur dioxide in flue gas and application thereof 河北精致科技有限公司 2022-04-29 CN claimed
CN-114159946-A Absorbent for removing sulfur dioxide in flue gas and application thereof 河北精致科技有限公司 2022-03-11 CN claimed
CN-113784997-A Rigid polyurethane foam suitable for use as a panel insulation material 科思创有限公司 2021-12-10 CN claimed
CN-113748150-A Rigid polyurethane foams suitable for use as board insulation 科思创有限公司 2021-12-03 CN claimed
CN-113557255-A Polyol blends and their use in the production of PUR-PIR foam-forming compositions 科思创有限公司 2021-10-26 CN claimed
CN-113490701-A Isocyanate-reactive HCFO-containing compositions, related foam-forming compositions and PUR-PIR foams 科思创有限公司 2021-10-08 CN claimed
CN-112262166-A Polyurethane foam-forming compositions 速的奥公司 2021-01-22 CN claimed
CN-107022103-B Foams and foamable compositions containing halogenated olefin blowing agents 霍尼韦尔国际公司 2020-11-27 CN claimed
US-8642669-B2 Foamable low-viscosity mixtures HENKEL AG & CO., KGAA (DE) 2014-02-04 US claimed
EP-2303941-B1 FOAMABLE LOW-VISCOSITY MIXTURES HENKEL AG & CO KGAA (DE) 2013-08-21 EP claimed
US-20120012505-A1 USE OF ALPHA-AMINO ETHERS FOR THE REMOVAL OF MERCAPTANS FROM HYDROCARBONS NALCO COMPANY 2012-01-19 US claimed
US-20110224319-A1 FOAMABLE LOW-VISCOSITY MIXTURES HENKEL AG & CO. KGAA (DE) 2011-09-15 US claimed
US-20110028640-A1 HARDENABLE COMPOSITIONS BASED ON SILYLATED POLYURETHANES HENKEL AG & CO. KGAA (DE) 2011-02-03 US claimed
CN-118236841-B Purifying method of flue gas absorbent 河北精致科技有限公司 2025-07-22 CN disclosed
US-20070270518-A1 Phase-Stable Polyurethane Prepolymers RATHOR AG (CH) 2007-11-22 US disclosed