Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691972 | 0.88 | KEAP1 (0.36) | KDM4EHSD17B10POLBGAATSHR | |
| SCHEMBL6689868 | 0.84 | EPHX2 (0.35) | KDM4EHSD17B10POLBGAATSHR | |
| SCHEMBL6690287 | 0.82 | KDM4E (0.40) | KDM4EHSD17B10POLBGAATSHR | |
| SCHEMBL347618 | 0.81 | USP2 (0.44) | KDM4EHSD17B10POLBGAATSHR | |
| SCHEMBL1467966 | 0.81 | TSHR (0.50) | KDM4EPOLBTSHRL3MBTL1GLA | |
| SCHEMBL6689574 | 0.79 | LMNA (0.31) | HRH3 | |
| SCHEMBL6693141 | 0.78 | POLB (0.58) | KDM4EHSD17B10POLBGAATSHR | |
| SCHEMBL3304899 | 0.78 | ALDH1A1 (0.43) | KDM4EPOLBGAATSHRUSP2 | |
| SCHEMBL26920081 | 0.77 | TDP1 (0.44) | POLBGAATSHRUSP2HRH3 | |
| SCHEMBL347311 | 0.77 | USP2 (0.41) | KDM4EHSD17B10POLBGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | disclosed |