SCHEMBL3476342

SCHEMBL3476342

Cn1ccc2cc(-c3ccc4oc(NC5CCCCCC5)nc4c3)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 18/20 1.00
PIK3CA P42336 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3474869 1.00 FAAH (1.00) FAAHPIK3CA
SCHEMBL3477026 0.99 FAAH (0.98) FAAHPIK3CA
SCHEMBL3478418 0.97 FAAH (0.94) FAAH
SCHEMBL3476608 0.91 FAAH (0.84) FAAHPIK3CA
SCHEMBL3476291 0.88 FAAH (0.78) FAAH
SCHEMBL3477383 0.86 FAAH (1.00) FAAHPIK3CA
SCHEMBL3476952 0.85 FAAH (0.74) FAAH
SCHEMBL3475214 0.85 FAAH (0.74) FAAH
SCHEMBL3477927 0.85 FAAH (0.74) FAAHPIK3CA
SCHEMBL3478096 0.84 FAAH (0.78) FAAHPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed