Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.74 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3474869 | 0.85 | FAAH (1.00) | FAAHPIK3CA | |
| SCHEMBL3476342 | 0.85 | FAAH (1.00) | FAAHPIK3CA | |
| SCHEMBL3477026 | 0.83 | FAAH (0.98) | FAAHPIK3CA | |
| SCHEMBL3476608 | 0.83 | FAAH (0.84) | FAAHPIK3CAHDAC6 | |
| SCHEMBL3475764 | 0.82 | FAAH (1.00) | FAAHPIK3CAHDAC6 | |
| SCHEMBL3478418 | 0.81 | FAAH (0.94) | FAAH | |
| SCHEMBL3478430 | 0.80 | FAAH (0.67) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477409 | 0.80 | FAAH (0.71) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3475379 | 0.79 | FAAH (0.66) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477307 | 0.79 | FAAH (0.66) | FAAHPIK3CAHDAC6ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |