Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FRK | P42685 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.44 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.44 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.44 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.44 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.44 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476466 | 1.00 | PRKD3 (0.44) | PRKD3MAP4K4FGFR1FRKMAPK8 | |
| SCHEMBL3476211 | 0.84 | CSNK1E (0.49) | PRKD3MAP4K4FGFR1FRKMAPK8 | |
| SCHEMBL3476214 | 0.84 | CSNK1E (0.49) | PRKD3MAP4K4FGFR1FRKMAPK8 | |
| SCHEMBL3475609 | 0.84 | FAAH (0.41) | SMN1; SMN2CYP3A4ALOX15LMNAHTT | |
| SCHEMBL3478564 | 0.84 | MAPK14 (0.46) | PRKD3MAP4K4FGFR1FRKMAPK8 | |
| SCHEMBL3475610 | 0.83 | FAAH (0.40) | SMN1; SMN2CYP3A4ALOX15LMNAHTT | |
| SCHEMBL3478399 | 0.80 | CSNK1E (0.66) | PRKD3MAP4K4FGFR1FRKMAPK8 | |
| SCHEMBL3478403 | 0.80 | CSNK1E (0.66) | PRKD3MAP4K4FGFR1FRKMAPK8 | |
| SCHEMBL3116900 | 0.77 | GRIA1 (0.47) | MAPK14MAPK13MAPK12MAPK11CSNK1E | |
| SCHEMBL13072854 | 0.77 | CSNK1E (0.66) | PRKD3MAP4K4FGFR1FRKMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130934-A2 | 2-CYCLOAMINO-5-(PYRIDIN-4-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-11-18 | — | — | WO | disclosed |