Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | HTR2C | P28335 | 3/20 | 0.59 |
| ▸ | HTR1D | P28221 | 2/20 | 0.59 |
| ▸ | HTR1B | P28222 | 2/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 1/20 | 0.59 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1308758 | 0.85 | MEN1 (0.62) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL349109 | 0.82 | SLC6A4 (0.58) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL6805445 | 0.82 | HTR2A (0.57) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL348936 | 0.81 | HTR2A (0.61) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL29521038 | 0.81 | MEN1 (0.62) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL3225554 | 0.81 | MEN1 (0.62) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL149254 | 0.81 | MEN1 (0.62) | MEN1KMT2AMAPTCYP3A4AHR | |
| Tryptamine SCHEMBL27810114 | 0.80 | HTR2A (0.86) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL6524121 | 0.78 | MEN1 (0.69) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL29413080 | 0.78 | MEN1 (0.69) | MEN1KMT2AMAPTCYP3A4AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801489-A1 | ACYLATED ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF AUTOIMMUNE DISORDERS | Flagship Pioneering Innovations V, Inc. (US) | 2021-04-14 | — | — | EP | claimed |
| WO-2020245629-A1 | MIXTURES AND COMPOSITIONS OF FLUENSULFONE AND AUXIN, AND USES THEREOF | ADAMA MAKHTESHIM LTD> (IL) | 2020-12-10 | — | — | WO | claimed |
| US-10654838-B2 | Aminopyridine compounds useful as inhibitors of protein prenylation | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2020-05-19 | — | — | US | claimed |
| EP-3204380-B1 | NOVEL AMINOPYRIDINE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN PRENYLATION | INST NAT SANTE RECH MED (FR) | 2019-08-07 | — | — | EP | claimed |
| CN-107513081-A | The acetyl glutamy Glucosamine propane of 2,2 2 indoles 3, it is synthesized, anti-inflammatory activity and application | 首都医科大学 | 2017-12-26 | — | — | CN | claimed |
| US-20170305892-A1 | NOVEL AMINOPYRIDINE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN PRENYLATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-10-26 | — | — | US | claimed |
| EP-3204380-A1 | NOVEL AMINOPYRIDINE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN PRENYLATION | Institut National de la Santé et de la Recherche Médicale (FR) | 2017-08-16 | — | — | EP | claimed |
| CN-107001315-A | It can be used as the novel aminopyridine compound of the inhibitor of protein prenylation | 国家健康与医学研究院 | 2017-08-01 | — | — | CN | claimed |
| CN-106946910-A | Parallel indoles acetyl derivatives of a kind of pyrans and its preparation method and application | 上海海洋大学 | 2017-07-14 | — | — | CN | claimed |
| CN-106537145-A | Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment | 麦特博隆股份有限公司 | 2017-03-22 | — | — | CN | claimed |
| EP-0480918-A1 | REDUCED SIZE LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1992-04-22 | — | — | EP | claimed |
| US-5068222-A | Polypeptides for treatment of cancer | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-26 | — | — | US | claimed |
| EP-0480918-A4 | REDUCED SIZE LHRH ANALOGS. | ABBOTT LAB (US) | 1991-06-04 | — | — | EP | claimed |
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |
| WO-1989007451-A1 | REDUCED SIZE LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | claimed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |
| EP-0315367-A2 | Polypeptides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-10 | — | — | EP | claimed |
| US-4563464-A | 2-Azabicyclo(2.2.2)octane derivatives and their use as immunosuppressive agents | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1986-01-07 | — | — | US | claimed |
| EP-0132964-A2 | 2-Azabicyclo[2.2.2]octane derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1985-02-13 | — | — | EP | claimed |
| US-3971736-A | HEXA- AND HEPTA-PEPTIDES, ANTIINFLAMMATORY, ANTIULCER, ANTIARTHRITIC | MERCK & CO., INC. (US) | 1976-07-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305892-A1 | NOVEL AMINOPYRIDINE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN PRENYLATION | RCE1, PTAR1, CDK2AP1 | MEN1 2611/4885KMT2A 3937/4885MAPT 3835/4885 |
| US-10654838-B2 | Aminopyridine compounds useful as inhibitors of protein prenylation | RCE1, PTAR1, CDK2AP1 | MEN1 2138/4885KMT2A 3735/4885MAPT 3654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.