Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524609 | 0.82 | MEN1 (0.70) | HTR2AHTR6CYP3A4HTR2CMPO | |
| SCHEMBL347688 | 0.82 | MEN1 (0.62) | HTR2AHTR6CYP3A4HTR2CMPO | |
| SCHEMBL4985934 | 0.80 | HTR2A (0.77) | HTR2AHTR6CYP3A4HTR2CMPO | |
| SCHEMBL18826588 | 0.80 | KMT2A (0.60) | HTR2AHTR6CYP3A4HTR2CMPO | |
| SCHEMBL10969880 | 0.80 | GFER (0.65) | HTR2AHTR6CYP3A4HTR2CMPO | |
| SCHEMBL31744670 | 0.80 | HTR2A (0.57) | HTR2AHTR6CYP3A4HTR2CMPO | |
| SCHEMBL348936 | 0.79 | HTR2A (0.61) | HTR2AHTR6CYP3A4HTR2CMPO | |
| Tryptamine SCHEMBL27810114 | 0.78 | HTR2A (0.86) | HTR2AHTR6CYP3A4HTR2CMPO | |
| SCHEMBL31744700 | 0.77 | PKM (0.75) | HTR2AHTR6CYP3A4HTR2CMPO | |
| SCHEMBL735580 | 0.76 | HTR2A (0.57) | HTR2AHTR6CYP3A4HTR2CMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770647-B2 | Bicyclic hydroxamates as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE) | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-03 | — | — | US | disclosed |