SCHEMBL3476986

SCHEMBL3476986

C=C[Si](C)(C)O[Si](C)(C)C(CCC)OC(=O)C(=C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3476344 0.89 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL3477370 0.88 TSHR (0.32) TSHR
SCHEMBL3477476 0.82 TSHR (0.35) TSHR
SCHEMBL16538029 0.80 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL3448578 0.79 TSHR (0.32) TSHR
SCHEMBL16537348 0.79 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL11490125 0.78 ALDH1A1 (0.30) ALDH1A1
SCHEMBL3476980 0.77
SCHEMBL17541578 0.75 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL7179413 0.75 TSHR (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4135623-B1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RXSIGHT INC (US) 2026-04-08 EP disclosed
US-20260069403-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE RXSIGHT, INC. (US) 2026-03-12 US disclosed
US-20240252311-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RXSIGHT, INC. 2024-08-01 US disclosed
EP-4294325-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE RxSight, Inc. (US) 2023-12-27 EP disclosed
EP-4135623-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RxSight, Inc. (US) 2023-02-22 EP disclosed
WO-2022177821-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE RXSIGHT, INC. (US) 2022-08-25 WO disclosed
WO-2021211888-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RXSIGHT, INC. (US) 2021-10-21 WO disclosed
US-20210322152-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RXSIGHT, INC. (US) 2021-10-21 US disclosed
US-20210251744-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE RXSIGHT, INC. (US) 2021-08-19 US disclosed
EP-2396355-B1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN INC (US) 2018-05-23 EP disclosed
US-8680172-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2014-03-25 US disclosed
US-20130245756-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS LILLY MING INTERNATIONAL, INC. 2013-09-19 US disclosed
US-8430928-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2013-04-30 US disclosed
US-20120245684-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2012-09-27 US disclosed
US-8222360-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2012-07-17 US disclosed
US-20100211170-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2010-08-19 US disclosed
WO-2010093823-A2 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2010-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069403-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE IGLV6-57, SMCHD1, UACA ALDH1A1 420/4885TSHR 819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.