SCHEMBL3477241

SCHEMBL3477241

CC(C)(Cc1cccc(F)c1)C(=O)C(C)(C)Cc1cccc(F)c1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.54
SLC1A1 P43005 2/20 0.46
MAOB P27338 2/20 0.44
TAAR1 Q96RJ0 3/20 0.43
FFAR1 O14842 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42
NR4A2 P43354 1/20 0.42
IDO1 P14902 1/20 0.42
AGXT P21549 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12913271 0.88 RIPK1 (0.52) RIPK1SLC1A1MAOBTAAR1FFAR1
SCHEMBL23430237 0.81 RIPK1 (0.49) RIPK1SLC1A1MAOBMEN1KMT2A
SCHEMBL28343170 0.79 TAAR1 (0.44) RIPK1SLC1A1MAOBTAAR1IDO1
SCHEMBL73801 0.79 TAAR1 (0.50) RIPK1MAOBTAAR1MEN1KMT2A
SCHEMBL3476733 0.79 RIPK1 (0.54) RIPK1MAOBTAAR1
SCHEMBL6340957 0.78 BLM (0.58) RIPK1SLC1A1MAOBTAAR1MEN1
SCHEMBL7271843 0.78 BLM (0.58) RIPK1SLC1A1MAOBTAAR1MEN1
SCHEMBL6340955 0.78 BLM (0.58) RIPK1SLC1A1MAOBTAAR1MEN1
SCHEMBL12913276 0.78 RIPK1 (0.50) RIPK1TAAR1MEN1KMT2AHCAR2
SCHEMBL28414876 0.77 RIPK1 (0.46) RIPK1SLC1A1MAOBTAAR1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101704950-B PASSI terpolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2013-07-31 CN claimed
EP-2233512-B1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF NINGBO INST MATERIALS TECHNOLOGY & ENG CAS (CN) 2013-03-20 EP claimed
CN-102030903-B Preparation method of polythioether ketone imide terpolymer NINGBO INST MAT TECH & ENG CAS 2013-03-06 CN claimed
CN-102030903-A Polythioether ketone imide terpolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2011-04-27 CN claimed
US-20110065891-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF CHANGCHUN HIPOLYKING CO.,LTD. (CN) 2011-03-17 US claimed
EP-2233512-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF Ningbo Institute Of Materials Technology And Engineering, Chinese Academy Of Sciences (CN) 2010-09-29 EP claimed
CN-101704950-A PASSI terpolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2010-05-12 CN claimed
CN-101531758-A Polythioetherimide and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2009-09-16 CN claimed
CN-101704950-B PASSI terpolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2013-07-31 CN disclosed
EP-2233512-B1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF NINGBO INST MATERIALS TECHNOLOGY & ENG CAS (CN) 2013-03-20 EP disclosed
CN-102030903-B Preparation method of polythioether ketone imide terpolymer NINGBO INST MAT TECH & ENG CAS 2013-03-06 CN disclosed
CN-102206343-B Polyarylenethioethernitrileimide copolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2012-10-03 CN disclosed
CN-102206343-A Polyarylenethioethernitrileimide copolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2011-10-05 CN disclosed
CN-102030903-A Polythioether ketone imide terpolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2011-04-27 CN disclosed
US-20110065891-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF CHANGCHUN HIPOLYKING CO.,LTD. (CN) 2011-03-17 US disclosed
EP-2233512-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF Ningbo Institute Of Materials Technology And Engineering, Chinese Academy Of Sciences (CN) 2010-09-29 EP disclosed
CN-101704950-A PASSI terpolymer and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2010-05-12 CN disclosed
CN-101531758-A Polythioetherimide and preparation method thereof NINGBO INST MAT TECH & ENG CAS 2009-09-16 CN disclosed