SCHEMBL3476733

SCHEMBL3476733

CC(C)(Cc1cccc(Cl)c1)C(=O)C(C)(C)Cc1cccc(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.54
PNMT P11086 2/20 0.49
KIF11 P52732 1/20 0.47
CTBP2 P56545 1/20 0.46
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
PKM P14618 1/20 0.44
TAAR1 Q96RJ0 3/20 0.43
HTR3E A5X5Y0 2/20 0.43
HTR3B O95264 2/20 0.43
HTR3A P46098 2/20 0.43
HTR3D Q70Z44 2/20 0.43
HTR3C Q8WXA8 2/20 0.43
PIK3CA P42336 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21313898 0.88 RIPK1 (0.52) RIPK1PNMTKIF11CTBP2PKM
SCHEMBL8324906 0.79 MAOB (0.52) RIPK1PNMTMAOBTAAR1HTR3E
SCHEMBL28346002 0.79 PNMT (0.50) RIPK1PNMTTAAR1HTR3EHTR3B
SCHEMBL73643 0.79 PNMT (0.54) RIPK1PNMTTAAR1HTR3EHTR3B
SCHEMBL3477241 0.79 RIPK1 (0.54) RIPK1MAOBTAAR1
SCHEMBL4340077 0.78 BLM (0.58) RIPK1PNMTKIF11CTBP2PKM
SCHEMBL27699328 0.78 BLM (0.58) RIPK1PNMTKIF11CTBP2PKM
SCHEMBL6340256 0.78 BLM (0.58) RIPK1PNMTKIF11CTBP2PKM
SCHEMBL28477012 0.78 PNMT (0.48) RIPK1PNMTMAOBTAAR1HTR3E
SCHEMBL4328573 0.77 SLC6A4 (0.55) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2233512-B1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF NINGBO INST MATERIALS TECHNOLOGY & ENG CAS (CN) 2013-03-20 EP claimed
US-20110065891-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF CHANGCHUN HIPOLYKING CO.,LTD. (CN) 2011-03-17 US claimed
EP-2233512-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF Ningbo Institute Of Materials Technology And Engineering, Chinese Academy Of Sciences (CN) 2010-09-29 EP claimed
EP-2233512-B1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF NINGBO INST MATERIALS TECHNOLOGY & ENG CAS (CN) 2013-03-20 EP disclosed
US-20110065891-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF CHANGCHUN HIPOLYKING CO.,LTD. (CN) 2011-03-17 US disclosed
EP-2233512-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF Ningbo Institute Of Materials Technology And Engineering, Chinese Academy Of Sciences (CN) 2010-09-29 EP disclosed