Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476299 | 0.84 | FAAH (0.73) | FAAHPIK3CAHDAC6RPS6KA2HPGD | |
| SCHEMBL3477307 | 0.84 | FAAH (0.66) | FAAHPIK3CAHDAC6MAPTELANE | |
| SCHEMBL3476255 | 0.83 | FAAH (0.62) | FAAHPIK3CAHDAC6RPS6KA2SSTR5 | |
| SCHEMBL13436687 | 0.81 | FAAH (0.59) | FAAHPIK3CAHDAC6RPS6KA2ELANE | |
| SCHEMBL3474867 | 0.79 | FAAH (0.69) | FAAHPIK3CAHDAC6RPS6KA2ELANE | |
| SCHEMBL3477435 | 0.79 | FAAH (0.75) | FAAHPIK3CAHDAC6RPS6KA2ALDH1A1 | |
| SCHEMBL16666112 | 0.79 | HDAC6 (0.60) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477409 | 0.78 | FAAH (0.71) | FAAHPIK3CAHDAC6MAPTELANE | |
| SCHEMBL3475819 | 0.78 | FAAH (0.65) | FAAHPIK3CAHDAC6ELANEALDH1A1 | |
| SCHEMBL3477061 | 0.77 | FAAH (0.58) | FAAHPIK3CAHDAC6MAPTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |