Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477713 | 0.88 | FAAH (0.60) | FAAHPIK3CAHDAC6ELANEBRD4 | |
| SCHEMBL3478462 | 0.86 | FAAH (0.59) | FAAHPIK3CAHDAC6IRAK4ELANE | |
| SCHEMBL3477722 | 0.81 | FAAH (0.59) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477428 | 0.78 | FAAH (0.64) | FAAHPIK3CAHDAC6IRAK4ELANE | |
| SCHEMBL3475662 | 0.78 | FAAH (0.61) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477307 | 0.77 | FAAH (0.66) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477494 | 0.77 | FAAH (0.60) | FAAHPIK3CAHDAC6IRAK4ELANE | |
| SCHEMBL3477409 | 0.76 | FAAH (0.71) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3475819 | 0.76 | FAAH (0.65) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL21318638 | 0.76 | IRAK4 (0.77) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |