SCHEMBL3477499

SCHEMBL3477499

Cn1ccc2cc(-c3ccc4oc(Nc5cccs5)nc4c3)ccc21

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 19/20 0.70
DYRK1A Q13627 1/20 0.48
CLK4 Q9HAZ1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3476992 0.82 FAAH (1.00) FAAH
SCHEMBL3478143 0.81 FAAH (0.81) FAAH
SCHEMBL3478456 0.81 FAAH (0.72) FAAH
SCHEMBL3478158 0.80 FAAH (0.66) FAAH
SCHEMBL3478203 0.79 FAAH (1.00) FAAH
SCHEMBL3477039 0.78 FAAH (1.00) FAAH
SCHEMBL13436722 0.78 FAAH (0.80) FAAH
SCHEMBL13436716 0.78 FAAH (1.00) FAAHCLK4
SCHEMBL3477846 0.78 FAAH (0.76) FAAHCLK4
SCHEMBL3477560 0.78 FAAH (0.79) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed